Translation from bats to humans beyond infectious diseases
Bats are attracting the greatest attention recently as a putative reservoir of SARS-CoV-2 responsible for the COVID-19 pandemic. However, less known to the public, bats also have several unique traits of high value to human health. The lessons we learn from bats can potentially help us fight many hu...
Saved in:
Published in | The Journal of experimental medicine Vol. 218; no. 9 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
United States
Rockefeller University Press
06.09.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Bats are attracting the greatest attention recently as a putative reservoir of SARS-CoV-2 responsible for the COVID-19 pandemic. However, less known to the public, bats also have several unique traits of high value to human health. The lessons we learn from bats can potentially help us fight many human diseases, including infection, aging, and cancer. |
---|---|
AbstractList | Bats are attracting the greatest attention recently as a putative reservoir of SARS-CoV-2 responsible for the COVID-19 pandemic. However, less known to the public, bats also have several unique traits of high value to human health. The lessons we learn from bats can potentially help us fight many human diseases, including infection, aging, and cancer. Ahn and Wang discuss the translational potential of the bat model for treating human diseases. Bats are attracting the greatest attention recently as a putative reservoir of SARS-CoV-2 responsible for the COVID-19 pandemic. However, less known to the public, bats also have several unique traits of high value to human health. The lessons we learn from bats can potentially help us fight many human diseases, including infection, aging, and cancer. |
Author | Ahn, Matae Wang, Lin-Fa |
AuthorAffiliation | Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore |
AuthorAffiliation_xml | – name: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore |
Author_xml | – sequence: 1 givenname: Matae surname: Ahn fullname: Ahn, Matae organization: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore – sequence: 2 givenname: Lin-Fa orcidid: 0000-0003-2752-0535 surname: Wang fullname: Wang, Lin-Fa organization: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34313734$$D View this record in MEDLINE/PubMed |
BookMark | eNpVkDtPwzAURi1URB-wMaOMDKTYvnbqMCChipdUiaXMlu3YNFVilzhB6r8nVR-C6Q7f0XfvPWM08MFbhK4JnhIs2P3a1lOKKSGUwhkaEc5wmnMQAzTCmNKUYDwbonGMa4wJYzy7QENgQGAGbIQelo3ysVJtGXzimlAnWrUxaUOy6uo-SbTdBl8kpXfW9FAXk6KMVkUbL9G5U1W0V4c5QZ8vz8v5W7r4eH2fPy1SA4K1qXGQU2F4BkZZ57KCQu44zyxmWjvGNKcEdF4YS3NFDaWCcpsLjoXAVGMNE_S47910urY959tGVXLTlLVqtjKoUv5PfLmSX-FHCiBCAPQFt4eCJnx3NrayLqOxVaW87R-SlPfngMBkh97tUdOEGBvrTmsIljvdstctj7p7_ObvaSf46Bd-AQF4fb0 |
CitedBy_id | crossref_primary_10_1016_j_cell_2023_03_036 crossref_primary_10_1016_j_it_2024_01_007 crossref_primary_10_3390_v14010150 crossref_primary_10_3390_d16040192 |
Cites_doi | 10.1126/sciadv.aao0926 10.1016/j.coviro.2011.10.013 10.1038/s41579-020-00459-7 10.1038/srep21722 10.1038/s41598-019-57212-1 10.1073/pnas.2003352117 10.1242/jeb.57.2.317 10.1046/j.1474-9728.2002.00020.x 10.1016/S0140-6736(20)30350-0 10.1038/s41586-020-2012-7 10.1038/s41568-018-0004-9 10.1038/s41564-019-0371-3 10.1038/s41586-020-03128-0 10.1016/j.cell.2014.12.003 10.1038/nature22975 |
ContentType | Journal Article |
Copyright | 2021 Ahn and Wang. 2021 Ahn and Wang 2021 |
Copyright_xml | – notice: 2021 Ahn and Wang. – notice: 2021 Ahn and Wang 2021 |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 5PM |
DOI | 10.1084/jem.20211223 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic PubMed Central (Full Participant titles) |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE MEDLINE - Academic CrossRef |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
DocumentTitleAlternate | Translation from bats to humans beyond infectious diseases |
EISSN | 1540-9538 |
ExternalDocumentID | 10_1084_jem_20211223 34313734 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GrantInformation_xml | – fundername: National Medical Research Council grantid: MOH-000386 – fundername: Ministry of Education grantid: MOE2019-T2-2-130 – fundername: Singapore National Research Foundation grantid: NRF-CRP10-2012-05 – fundername: ; grantid: NRF-CRP10-2012-05; NRF2016NRF-NSFC002-013 – fundername: ; grantid: MOH-000386; OFIRG19nov-0050 – fundername: ; grantid: MOE2019-T2-2-130 |
GroupedDBID | --- -~X 18M 29K 2WC 36B 4.4 53G 5GY 5RE 5VS ABOCM ABZEH ACGFO ACNCT ACPRK ADBBV AENEX AFOSN AFRAH ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BTFSW C45 CGR CS3 CUY CVF D-I DIK DU5 E3Z EBS ECM EIF EMB F5P F9R FRP GX1 H13 HYE IH2 KQ8 L7B N9A NPM O5R O5S OK1 P2P P6G R.V RHF RHI RPM SJN TR2 TRP UHB W8F WOQ AAYXX CITATION 7X8 5PM |
ID | FETCH-LOGICAL-c384t-cf3928c563caeff6d239f556e04bbf44b5213b9dce29a2c22825e98508802b0b3 |
ISSN | 0022-1007 |
IngestDate | Tue Sep 17 21:20:53 EDT 2024 Fri Oct 25 22:20:07 EDT 2024 Thu Nov 21 21:19:54 EST 2024 Sat Sep 28 08:20:52 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 9 |
Language | English |
License | 2021 Ahn and Wang. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c384t-cf3928c563caeff6d239f556e04bbf44b5213b9dce29a2c22825e98508802b0b3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0003-2752-0535 |
OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC8318833 |
PMID | 34313734 |
PQID | 2555638013 |
PQPubID | 23479 |
ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_8318833 proquest_miscellaneous_2555638013 crossref_primary_10_1084_jem_20211223 pubmed_primary_34313734 |
PublicationCentury | 2000 |
PublicationDate | 2021-09-06 |
PublicationDateYYYYMMDD | 2021-09-06 |
PublicationDate_xml | – month: 09 year: 2021 text: 2021-09-06 day: 06 |
PublicationDecade | 2020 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | The Journal of experimental medicine |
PublicationTitleAlternate | J Exp Med |
PublicationYear | 2021 |
Publisher | Rockefeller University Press |
Publisher_xml | – name: Rockefeller University Press |
References | Ahn (2023072815171656300_bib1) 2016 Gamage (2023072815171656300_bib4) 2020 Wilkinson (2023072815171656300_bib14) 2002 Seluanov (2023072815171656300_bib10) 2018 Irving (2023072815171656300_bib7) 2021 Mandl (2023072815171656300_bib8) 2015 Ahn (2023072815171656300_bib2) 2019 Hu (2023072815171656300_bib6) 2021 Thomas (2023072815171656300_bib11) 1972 Foley (2023072815171656300_bib3) 2018 Zhou (2023072815171656300_bib15) 2020 Goh (2023072815171656300_bib5) 2020 Olival (2023072815171656300_bib9) 2017 Wang (2023072815171656300_bib13) 2020 Wang (2023072815171656300_bib12) 2011 |
References_xml | – year: 2018 ident: 2023072815171656300_bib3 publication-title: Sci. Adv. doi: 10.1126/sciadv.aao0926 contributor: fullname: Foley – year: 2011 ident: 2023072815171656300_bib12 publication-title: Curr. Opin. Virol. doi: 10.1016/j.coviro.2011.10.013 contributor: fullname: Wang – year: 2021 ident: 2023072815171656300_bib6 publication-title: Nat. Rev. Microbiol. doi: 10.1038/s41579-020-00459-7 contributor: fullname: Hu – year: 2016 ident: 2023072815171656300_bib1 publication-title: Sci. Rep. doi: 10.1038/srep21722 contributor: fullname: Ahn – year: 2020 ident: 2023072815171656300_bib4 publication-title: Sci. Rep. doi: 10.1038/s41598-019-57212-1 contributor: fullname: Gamage – year: 2020 ident: 2023072815171656300_bib5 publication-title: Proc. Natl. Acad. Sci. USA. doi: 10.1073/pnas.2003352117 contributor: fullname: Goh – year: 1972 ident: 2023072815171656300_bib11 publication-title: J. Exp. Biol. doi: 10.1242/jeb.57.2.317 contributor: fullname: Thomas – year: 2002 ident: 2023072815171656300_bib14 publication-title: Aging Cell. doi: 10.1046/j.1474-9728.2002.00020.x contributor: fullname: Wilkinson – year: 2020 ident: 2023072815171656300_bib13 publication-title: Lancet. doi: 10.1016/S0140-6736(20)30350-0 contributor: fullname: Wang – year: 2020 ident: 2023072815171656300_bib15 publication-title: Nature. doi: 10.1038/s41586-020-2012-7 contributor: fullname: Zhou – year: 2018 ident: 2023072815171656300_bib10 publication-title: Nat. Rev. Cancer. doi: 10.1038/s41568-018-0004-9 contributor: fullname: Seluanov – year: 2019 ident: 2023072815171656300_bib2 publication-title: Nat. Microbiol. doi: 10.1038/s41564-019-0371-3 contributor: fullname: Ahn – year: 2021 ident: 2023072815171656300_bib7 publication-title: Nature. doi: 10.1038/s41586-020-03128-0 contributor: fullname: Irving – year: 2015 ident: 2023072815171656300_bib8 publication-title: Cell. doi: 10.1016/j.cell.2014.12.003 contributor: fullname: Mandl – year: 2017 ident: 2023072815171656300_bib9 publication-title: Nature. doi: 10.1038/nature22975 contributor: fullname: Olival |
SSID | ssj0014456 |
Score | 2.4477272 |
Snippet | Bats are attracting the greatest attention recently as a putative reservoir of SARS-CoV-2 responsible for the COVID-19 pandemic. However, less known to the... Ahn and Wang discuss the translational potential of the bat model for treating human diseases. Bats are attracting the greatest attention recently as a... |
SourceID | pubmedcentral proquest crossref pubmed |
SourceType | Open Access Repository Aggregation Database Index Database |
SubjectTerms | Animals Animals, Laboratory Chiroptera - physiology Chiroptera - virology COVID-19 Disease Models, Animal Disease Resistance - physiology Humans Infectious Disease and Host Defense Innate Immunity and Inflammation Viewpoint |
Title | Translation from bats to humans beyond infectious diseases |
URI | https://www.ncbi.nlm.nih.gov/pubmed/34313734 https://search.proquest.com/docview/2555638013 https://pubmed.ncbi.nlm.nih.gov/PMC8318833 |
Volume | 218 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1JS-RAFC5GB8SLOOPWs1GCcxqi6VrSFW8yzEwz0J4U-hbyUhUUJC12-uKv99WSrfWgXkJIp9KV94VX36u3EXIST8AkoCGSaiwjtDdMlGooI620kRrVoy7sfsfsMplei_9zOe9a-rnskhpOi8cX80regypeQ1xtluwbkG0fihfwHPHFIyKMx9dhbBeauxAuaPNEIK9dxQbXeW_5C3x6ShNwtVo2_phln5N22WGOlw5q_q-73i9ufOxvXuedUydsOaNZGwWNH7YR2NjFSSV91YhWqQ2Z8AtD0IYitv5d1VeXrNOXqxAR_kwNx0pYNWxsqj9amMynFA-rXa-tQm1soPOKK5Hh6KwZvUE-2kKHtjfCv3kbwoO2oOvO2049JDbg6LP-fw8pxzM7Yj0ctscvrnbJTgCAXniUP5EPpvpMtmZB_nvkvAc2tWBTCzatF9SDTT3YtAObNmDvk-u_f65-T6PQ-CIquBJ1VJTIWlUhE17kpiwTzXhaSpmYWACUQgByLg4pTpilOSuYzT82qbJcO2YQAz8gm9WiMkeEAlpQMSv1WBkQcpyngPYB6HiiNXCpyxH52cgmu_f1TbKXEBiR40ZwGSog61XKK4PvkqFNihNFooP3HHpBtk_iSE_5hIsRmQxE3N5gi5sPf6lub1yRc4WLjeL8yyvn95Vsd1_1N7JZP6zMd6SLNfxw38wTviNruw |
link.rule.ids | 230,314,780,784,885,27924,27925 |
linkProvider | Geneva Foundation for Medical Education and Research |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Translation+from+bats+to+humans+beyond+infectious+diseases&rft.jtitle=The+Journal+of+experimental+medicine&rft.au=Ahn%2C+Matae&rft.au=Wang%2C+Lin-Fa&rft.date=2021-09-06&rft.issn=0022-1007&rft.eissn=1540-9538&rft.volume=218&rft.issue=9&rft_id=info:doi/10.1084%2Fjem.20211223&rft.externalDBID=n%2Fa&rft.externalDocID=10_1084_jem_20211223 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-1007&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-1007&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-1007&client=summon |