Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19 - Wilk, Aaron J.; Lee, Madeline J.; Wei, Bei; Parks, Benjamin; Pi, Ruoxi; Martínez-Colón, Giovanny J.; Ranganath, Thanmayi; Zhao, Nancy Q.; Taylor, Shalina; Becker, Winston; Ranganath, Thanmayi; Zhao, Nancy Q.; et al. (The Journal of experimental medicine, 2021)
Keywords: Adult; Aged; Case-Control Studies; Covid-19; COVID-19 - blood; COVID-19 - genetics; COVID-19 - immunology; COVID-19 - mortality; Cytokines - genetics; Epigenesis, Genetic; Female; Hematopoiesis; Humans; Immunity, Innate - physiology; Infectious Disease and Host Defense; Innate Immunity and Inflammation; Killer Cells, Natural - pathology; Killer Cells, Natural - virology; Male; Middle Aged; Monocytes - pathology; Monocytes - virology; Neutrophils - pathology; Neutrophils - virology; NF-kappa B - metabolism; Proteomics; Severity of Illness Index; Single-Cell Analysis