Systemic or Vaginal Hormone Therapy After Early Breast Cancer: A Danish Observational Cohort Study

• Published in: JNCI : Journal of the National Cancer Institute Vol. 114; no. 10; pp. 1347 - 1354
• Main Authors: Cold, Søren, Cold, Frederik, Jensen, Maj-Britt, Cronin-Fenton, Deirdre, Christiansen, Peer, Ejlertsen, Bent
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 06.10.2022
• Subjects: Aromatase Inhibitors - therapeutic use; Breast Neoplasms - chemically induced; Breast Neoplasms - drug therapy; Breast Neoplasms - epidemiology; Cohort Studies; Denmark - epidemiology; Editor's Choice; Estrogen Replacement Therapy - adverse effects; Estrogens; Female; Hormone Replacement Therapy - adverse effects; Humans; Menopause; Receptors, Estrogen; Denmark

Women treated for breast cancer (BC) often suffer genitourinary syndrome of menopause. These symptoms may be alleviated by vaginal estrogen therapy (VET) or menopausal hormone therapy (MHT). However, there are concerns of risks of recurrence of BC and death following treatment. Our study included lo...