Relationships Between Airflow Obstruction and Quantitative CT Measurements of Emphysema, Air Trapping, and Airways in Subjects With and Without Chronic Obstructive Pulmonary Disease

• Published in: American journal of roentgenology (1976) Vol. 201; no. 3; pp. W460 - W470
• Main Authors: Schroeder, Joyce D., McKenzie, Alexander S., Zach, Jordan A., Wilson, Carla G., Curran-Everett, Douglas, Stinson, Douglas S., Newell, John D., Lynch, David A.
• Format: Journal Article
• Language: English
• Published: United States 01.09.2013
• Subjects: Aged; Aged, 80 and over; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive - diagnostic imaging; Pulmonary Disease, Chronic Obstructive - physiopathology; Pulmonary Emphysema - diagnostic imaging; Pulmonary Emphysema - physiopathology; Radiographic Image Interpretation, Computer-Assisted; Risk Factors; Severity of Illness Index; Smoking - physiopathology; Spirometry; Tomography, X-Ray Computed - methods; Vital Capacity

This study evaluates the relationships between quantitative CT (QCT) and spirometric measurements of disease severity in cigarette smokers with and without chronic obstructive pulmonary disease (COPD). Inspiratory and expiratory CT scans of 4062 subjects in the Genetic Epidemiology of COPD (COPDGene...