Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance - Deakyne, Julianna S.; Malecka, Kimberly A.; Messick, Troy E.; Lieberman, Paul M. (Journal of virology, 2017)
Keywords: Binding Sites - genetics; Cell Line, Tumor; Crystallography, X-Ray; DNA Replication - genetics; DNA, Viral - genetics; DNA-Binding Proteins - genetics; Epstein-Barr Virus Nuclear Antigens - genetics; Epstein-Barr Virus Nuclear Antigens - metabolism; Genome and Regulation of Viral Gene Expression; HEK293 Cells; HeLa Cells; Herpesvirus 4, Human - genetics; Herpesvirus 4, Human - growth & development; Histones - metabolism; Humans; Multiprotein Complexes - metabolism; Origin Recognition Complex - genetics; Plasmids - genetics; Protein Structure, Tertiary; Replication Origin - genetics; Virus Replication - genetics; episome maintenance; DNA-binding domain; viral latency; oligomers; hexameric ring; EBNA1; Epstein-Barr virus; OriP; cooperative binding