Changes in Nuclear Receptor and Vitellogenin Gene Expression in Response to Steroids and Heavy Metal in Caenorhabditis elegans

• Published in: Integrative and comparative biology Vol. 45; no. 1; pp. 61 - 71
• Main Authors: Novillo, Apolonia, Won, Seung-Jae, Li, Christine, Callard, Ian P.
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 2005; Society for Integrative and Comparative Biology
• Subjects: Cadmium; Cholesterols; Endocrinology and Immunology of Invertebrate Phyla; Gene expression; Gene expression regulation; Genes; Genomes; Nematodes; Nuclear receptors; Steroids; Vertebrates

To gain basic understanding of the reproductive and developmental effects of endocrine disrupting chemicals in invertebrates, we have used C. elegans as an animal model. The completion of the C. elegans genome sequence brings to bear microarray analysis as a tool for these studies. We previously sho...