Effects of Withania somnifera on Cortisol Levels in Stressed Human Subjects: A Systematic Review

• Published in: Nutrients Vol. 15; no. 24; p. 5015
• Main Authors: Della Porta, Matteo, Maier, Jeanette A., Cazzola, Roberta
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 05.12.2023
• Subjects: antioxidants; Antioxidants - pharmacology; Anxiety; cortisol; Hormones; Human subjects; Humans; Hydrocortisone; Infertility; Insomnia; medicinal plants; meta-analysis; Plant Extracts - therapeutic use; Plants, Medicinal; secretion; Sleep; Stress; Systematic review; Withania; Withania somnifera; adrenal function; ashwagandha; stress; adaptogens; withanolides

Background: Withania somnifera (WS), a popular medicinal plant of the Solanaceae family, contains active ingredients with antioxidant, anti-inflammatory, immunomodulatory, and anti-stress activities. However, its precise mechanisms of action and optimal use as a supplement are not yet fully understo...