In Vitro and In Vivo Inhibition of the Infectivity of Human Enterovirus 71 by a Sulfonated Food Azo Dye, Brilliant Black BN

• Published in: Journal of virology Vol. 93; no. 17
• Main Authors: Meng, Tao, Jia, Qiang, Wong, Sek-Man, Chua, Kaw-Bing
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.09.2019
• Subjects: Vaccines and Antiviral Agents; AG129 mouse; sulfonate; virus attachment factors; human enterovirus; food azo dye; virus entry; antiviral agent; hand foot and mouth disease

Hand, foot, and mouth disease (HFMD), a highly contagious disease in children, is caused by human enteroviruses, including enterovirus 71 (EV71), coxsackievirus A16 (CVA16), and coxsackievirus A6 (CVA6). Although HFMD is usually mild and self-limiting, EV71 infection occasionally leads to fatal neur...