Increased mortality in septic shock with the 4G/4G genotype of plasminogen activator inhibitor 1 in patients of white descent - García-Segarra, Gloria; Espinosa, Gerard; Tassies, Dolors; Oriola, Josep; Aibar, Jesús; Bové, Albert; Castro, Pedro; Reverter, Joan-Carles; Nicolás, Josep-Maria (Intensive care medicine, 2007)
Keywords: Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Antigens; Biological and medical sciences; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Blood. Blood coagulation. Reticuloendothelial system; Dimers; Epidemiology; Failure; Female; Gene polymorphism; Genotype & phenotype; Genotyping; Homozygotes; Hospital Mortality; Hospitals; Humans; Infections; Inflammation; Inflammatory response; Intensive care; Intensive care medicine; Intensive Care Units; Interleukin 1; Male; Medical Records; Medical sciences; Middle Aged; Mortality; Multiple Organ Failure - genetics; Patients; Pharmacology. Drug treatments; Physiology; Plasminogen Activator Inhibitor 1 - genetics; Plasminogen activator inhibitors; Polymorphism; Polymorphism, Genetic; Sepsis; Septic shock; Shock, Septic - genetics; Shock, Septic - mortality; Spain; Systemic inflammatory response syndrome; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Tumor necrosis factor; Tumor necrosis factor-TNF; Whites - genetics; Spain; Shock; Human; Septic shock, Organ failure, Fibrinolysis; Intensive care; Mortality; Genotype; Polymorphisms; Fibrinolysis; Infection; Plasminogen activator inhibitor 1; Plasminogen; Caucasoid; Resuscitation; Polymorphism