Real-time measurements of membrane surface dynamics on macrophages and the phagocytosis of Leishmania parasites
Defocusing microscopy was used for real-time observation and quantification of membrane surface dynamics in murine bone marrow macrophages. Small random membrane fluctuations (SRMF), possibly metabolic driven, were detected uniformly over all membrane surface. Morphological and dynamical parameters...
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| Published in | Experimental cell research Vol. 303; no. 2; pp. 207 - 217 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
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United States
Elsevier Inc
15.02.2005
Elsevier BV |
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| Abstract | Defocusing microscopy was used for real-time observation and quantification of membrane surface dynamics in murine bone marrow macrophages. Small random membrane fluctuations (SRMF), possibly metabolic driven, were detected uniformly over all membrane surface. Morphological and dynamical parameters of ruffles, such as shape, dimensions, and velocity of propagation, were analyzed. Optical tweezers were used to promote phagocytosis of single
Leishmania amazonensis amastigotes by selected macrophages. Analysis of ruffling activity on the macrophages before and during phagocytosis of the parasites indicated that increased ruffling response near forming phagosomes, most likely induced by the parasite, accelerates phagocytosis. The effects of temperature decrease on the dynamics of membrane surface fluctuations and on the phagocytosis of parasites were used to determine the overall activation energies involved in these processes. The values obtained support the existence of strong correlation between membrane motility and phagocytic capacity. |
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| AbstractList | Defocusing microscopy was used for real-time observation and quantification of membrane surface dynamics in murine bone marrow macrophages. Small random membrane fluctuations (SRMF), possibly metabolic driven, were detected uniformly over all membrane surface. Morphological and dynamical parameters of ruffles, such as shape, dimensions, and velocity of propagation, were analyzed. Optical tweezers were used to promote phagocytosis of single
Leishmania amazonensis amastigotes by selected macrophages. Analysis of ruffling activity on the macrophages before and during phagocytosis of the parasites indicated that increased ruffling response near forming phagosomes, most likely induced by the parasite, accelerates phagocytosis. The effects of temperature decrease on the dynamics of membrane surface fluctuations and on the phagocytosis of parasites were used to determine the overall activation energies involved in these processes. The values obtained support the existence of strong correlation between membrane motility and phagocytic capacity. Defocusing microscopy was used for real-time observation and quantification of membrane surface dynamics in murine bone marrow macrophages. Small random membrane fluctuations (SRMF), possibly metabolic driven, were detected uniformly over all membrane surface. Morphological and dynamical parameters of ruffles, such as shape, dimensions, and velocity of propagation, were analyzed. Optical tweezers were used to promote phagocytosis of single Leishmania amazonensis amastigotes by selected macrophages. Analysis of ruffling activity on the macrophages before and during phagocytosis of the parasites indicated that increased ruffling response near forming phagosomes, most likely induced by the parasite, accelerates phagocytosis. The effects of temperature decrease on the dynamics of membrane surface fluctuations and on the phagocytosis of parasites were used to determine the overall activation energies involved in these processes. The values obtained support the existence of strong correlation between membrane motility and phagocytic capacity. Defocusing microscopy was used for real-time observation and quantification of membrane surface dynamics in murine bone marrow macrophages. Small random membrane fluctuations (SRMF), possibly metabolic driven, were detected uniformly over all membrane surface. Morphological and dynamical parameters of ruffles, such as shape, dimensions, and velocity of propagation, were analyzed. Optical tweezers were used to promote phagocytosis of single Leishmania amazonensis amastigotes by selected macrophages. Analysis of ruffling activity on the macrophages before and during phagocytosis of the parasites indicated that increased ruffling response near forming phagosomes, most likely induced by the parasite, accelerates phagocytosis. The effects of temperature decrease on the dynamics of membrane surface fluctuations and on the phagocytosis of parasites were used to determine the overall activation energies involved in these processes. The values obtained support the existence of strong correlation between membrane motility and phagocytic capacity. [PUBLICATION ABSTRACT] |
| Author | Neto, José Coelho Agero, Ubirajara Gazzinelli, Ricardo T. Mesquita, Oscar N. Oliveira, Diogo C.P. |
| Author_xml | – sequence: 1 givenname: José Coelho surname: Neto fullname: Neto, José Coelho email: rabbit@fisica.ufmg.br organization: Departamento de Física, ICEx, Universidade Federal de Minas Gerais, CEP 30123-970, Belo Horizonte, Minas Gerais, Brasil – sequence: 2 givenname: Ubirajara surname: Agero fullname: Agero, Ubirajara organization: Departamento de Física, ICEx, Universidade Federal de Minas Gerais, CEP 30123-970, Belo Horizonte, Minas Gerais, Brasil – sequence: 3 givenname: Diogo C.P. surname: Oliveira fullname: Oliveira, Diogo C.P. organization: Centro de Pesquisas René Rachou, FIOCRUZ, CEP 30190-002, Belo Horizonte, Minas Gerais, Brasil – sequence: 4 givenname: Ricardo T. surname: Gazzinelli fullname: Gazzinelli, Ricardo T. organization: Departamento de Bioquímica e Imunologia, ICB, Universidade Federal de Minas, Gerais, CEP 30123-970, Belo Horizonte, Minas Gerais, Brasil – sequence: 5 givenname: Oscar N. surname: Mesquita fullname: Mesquita, Oscar N. organization: Departamento de Física, ICEx, Universidade Federal de Minas Gerais, CEP 30123-970, Belo Horizonte, Minas Gerais, Brasil |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/15652336$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1103_PhysRevLett_98_168103 crossref_primary_10_1103_PhysRevE_74_041903 crossref_primary_10_1063_1_3136842 crossref_primary_10_1590_S0001_37652007000100003 crossref_primary_10_1016_j_biosystems_2012_06_001 crossref_primary_10_1088_1742_5468_2006_11_P11007 crossref_primary_10_1103_PhysRevE_78_041911 crossref_primary_10_1529_biophysj_105_062224 crossref_primary_10_1186_1471_2180_13_107 crossref_primary_10_1063_1_4884420 crossref_primary_10_1063_1_2189010 crossref_primary_10_4049_jimmunol_175_5_3214 crossref_primary_10_1098_rsta_2007_2091 crossref_primary_10_1371_journal_pone_0097855 crossref_primary_10_1209_0295_5075_84_58008 crossref_primary_10_1016_j_bpj_2013_07_036 crossref_primary_10_1088_1361_6633_aa8730 crossref_primary_10_1529_biophysj_105_073783 |
| Cites_doi | 10.1016/0014-5793(91)81188-E 10.1016/S0092-8674(03)00120-X 10.1103/PhysRevE.67.051904 10.1091/mbc.11.9.2999 10.1242/jcs.115.11.2303 10.1016/S0021-9258(17)32873-9 10.1038/364639a0 10.1084/jem.139.2.323 10.1083/jcb.111.6.2513 10.1084/jem.144.3.788 10.1146/annurev.immunol.20.103001.114744 10.1242/jcs.112.18.2993 10.1073/pnas.94.10.5045 10.1016/S0960-9822(03)00160-X 10.1083/jcb.200206043 10.1007/BF00185092 10.1016/S0962-8924(00)88956-4 10.1016/S0006-3495(91)82104-X 10.1006/expr.1998.4232 10.1073/pnas.94.10.4853 10.1083/jcb.63.3.949 10.1016/S0962-8924(00)89101-1 10.1128/IAI.66.9.4331-4339.1998 10.1146/annurev.bi.46.070177.003321 10.1128/IAI.66.2.627-635.1998 10.1016/S0006-3495(92)81625-9 10.1084/jem.179.2.601 10.1073/pnas.79.15.4660 10.1016/S0962-8924(01)02237-1 10.1128/iai.61.4.1553-1558.1993 10.1016/0092-8674(84)90070-9 10.1146/annurev.immunol.17.1.593 10.1073/pnas.81.11.3414 10.1242/jcs.113.18.3329 10.1084/jem.142.5.1263 10.1083/jcb.200202050 10.1084/jem.141.6.1269 |
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| References | Underhill, Ozinsky (bib28) 2002; 20 Silverstein, Steinman, Cohn (bib21) 1977; 46 Tuvia, Almagor, Bitler, Levin, Korenstein, Yedgar (bib34) 1997; 94 Alpuche-Aranda, Racoosin, Swanson, Miller (bib6) 1994; 179 Krol, Grinfeldt, Levin, Smilgavichus (bib22) 1990; 19 Tuvia, Levin, Korenstein (bib33) 1992; 63 Felder, Elson (bib20) 1990; 111 Aderem, Underhill (bib27) 1999; 17 Griffin, Bianco, Silverstein (bib14) 1975; 141 Swanson, Baer (bib7) 1995; 5 Araki, Hatae, Yamada, Hirohashi (bib12) 2000; 113 Craig, Chen (bib4) 2003; 13 DeMali, Barlow, Burridge (bib3) 2002; 159 Swanson, Watts (bib8) 1995; 5 Courret, Fréhel, Gouhier, Pouchelet, Prina, Roux, Antonine (bib32) 2002; 115 Griffin, Griffin, Silverstein (bib16) 1976; 144 Horwitz (bib17) 1994; 36 Gordon, Yang, Korn (bib35) 1976; 251 Rittig, Schröppel, Seak, Sander, N'Diaye, Maridonneau-Parini, Solbach, Bogdan (bib19) 1998; 66 Griffin, Griffin, Leider, Silverstein (bib15) 1975; 142 Agero, Monken, Ropert, Gazzinelli, Mesquita (bib9) 2003; 67 Griffin, Silverstein (bib13) 1974; 139 Guy, Belosevic (bib29) 1993; 61 Francis, Ryan, Jones, Smith, Falkow (bib5) 1993; 364 Ballestrem, Wehrle-Haller, Hinz, Imhof (bib26) 2000; 11 Small, Stradal, Vignal, Rottner (bib1) 2002; 12 Rittig, Jagoda, Wilske, Murgia, Cinco, Repp, Burmester, Krause (bib18) 1998; 66 Fujiwara, Ritchie, Murakoshi, Jacobson, Kusumi (bib25) 2002; 157 . Levin, Korenstein (bib24) 1991; 60 Love, Mentink Kane, Mosser (bib30) 1998; 88 ImageJ 1.32 Alexander, Satoskar, Russel (bib31) 1999; 112 Steinman, Silver, Cohn (bib38) 1974; 63 Ashkin (bib10) 1997; 94 Mittelman, Levin, Korenstein (bib23) 1991; 293 Mastro, Babich, Taylor, Keith (bib37) 1984; 81 Pollard, Borisy (bib2) 2003; 112 Wang, Lanni, McNeil, Ware, Taylor (bib36) 1982; 79 Krol (10.1016/j.yexcr.2004.09.002_bib22) 1990; 19 DeMali (10.1016/j.yexcr.2004.09.002_bib3) 2002; 159 Love (10.1016/j.yexcr.2004.09.002_bib30) 1998; 88 Wang (10.1016/j.yexcr.2004.09.002_bib36) 1982; 79 Craig (10.1016/j.yexcr.2004.09.002_bib4) 2003; 13 Alpuche-Aranda (10.1016/j.yexcr.2004.09.002_bib6) 1994; 179 Mastro (10.1016/j.yexcr.2004.09.002_bib37) 1984; 81 Mittelman (10.1016/j.yexcr.2004.09.002_bib23) 1991; 293 Griffin (10.1016/j.yexcr.2004.09.002_bib15) 1975; 142 Silverstein (10.1016/j.yexcr.2004.09.002_bib21) 1977; 46 Courret (10.1016/j.yexcr.2004.09.002_bib32) 2002; 115 10.1016/j.yexcr.2004.09.002_bib11 Guy (10.1016/j.yexcr.2004.09.002_bib29) 1993; 61 Rittig (10.1016/j.yexcr.2004.09.002_bib19) 1998; 66 Ballestrem (10.1016/j.yexcr.2004.09.002_bib26) 2000; 11 Griffin (10.1016/j.yexcr.2004.09.002_bib14) 1975; 141 Aderem (10.1016/j.yexcr.2004.09.002_bib27) 1999; 17 Felder (10.1016/j.yexcr.2004.09.002_bib20) 1990; 111 Francis (10.1016/j.yexcr.2004.09.002_bib5) 1993; 364 Rittig (10.1016/j.yexcr.2004.09.002_bib18) 1998; 66 Underhill (10.1016/j.yexcr.2004.09.002_bib28) 2002; 20 Alexander (10.1016/j.yexcr.2004.09.002_bib31) 1999; 112 Agero (10.1016/j.yexcr.2004.09.002_bib9) 2003; 67 Horwitz (10.1016/j.yexcr.2004.09.002_bib17) 1994; 36 Small (10.1016/j.yexcr.2004.09.002_bib1) 2002; 12 Swanson (10.1016/j.yexcr.2004.09.002_bib7) 1995; 5 Griffin (10.1016/j.yexcr.2004.09.002_bib13) 1974; 139 Levin (10.1016/j.yexcr.2004.09.002_bib24) 1991; 60 Tuvia (10.1016/j.yexcr.2004.09.002_bib33) 1992; 63 Swanson (10.1016/j.yexcr.2004.09.002_bib8) 1995; 5 Tuvia (10.1016/j.yexcr.2004.09.002_bib34) 1997; 94 Pollard (10.1016/j.yexcr.2004.09.002_bib2) 2003; 112 Ashkin (10.1016/j.yexcr.2004.09.002_bib10) 1997; 94 Griffin (10.1016/j.yexcr.2004.09.002_bib16) 1976; 144 Steinman (10.1016/j.yexcr.2004.09.002_bib38) 1974; 63 Araki (10.1016/j.yexcr.2004.09.002_bib12) 2000; 113 Fujiwara (10.1016/j.yexcr.2004.09.002_bib25) 2002; 157 Gordon (10.1016/j.yexcr.2004.09.002_bib35) 1976; 251 |
| References_xml | – volume: 113 start-page: 3329 year: 2000 end-page: 3340 ident: bib12 article-title: Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging publication-title: J. Cell Sci. contributor: fullname: Hirohashi – volume: 112 start-page: 2993 year: 1999 end-page: 3002 ident: bib31 article-title: publication-title: J. Cell Sci. contributor: fullname: Russel – volume: 36 start-page: 27 year: 1994 end-page: 33 ident: bib17 article-title: Phagocytosis of the legionnaire's disease bacterium ( publication-title: Cell contributor: fullname: Horwitz – volume: 112 start-page: 453 year: 2003 end-page: 465 ident: bib2 article-title: Cellular motility driven by assembly and disassembly of actin filaments publication-title: Cell contributor: fullname: Borisy – volume: 5 start-page: 424 year: 1995 end-page: 428 ident: bib8 article-title: Macropinocytosis publication-title: Trends Cell Biol contributor: fullname: Watts – volume: 66 start-page: 4331 year: 1998 end-page: 4339 ident: bib19 article-title: Coiling phagocytosis of tripanosomatids and fungal cells publication-title: Infect. Immun. contributor: fullname: Bogdan – volume: 157 start-page: 1071 year: 2002 end-page: 1081 ident: bib25 article-title: Phospholipids undergo hop diffusion in compartmentalized cell membrane publication-title: J. Cell Biol. contributor: fullname: Kusumi – volume: 67 start-page: 051904 year: 2003 ident: bib9 article-title: Cell surface fluctuations studied with defocusing microscopy publication-title: Phys. Rev., E contributor: fullname: Mesquita – volume: 139 start-page: 323 year: 1974 end-page: 326 ident: bib13 article-title: Segmental response of the macrophage plasma membrane to a phagocytic stimulus publication-title: J. Exp. Med. contributor: fullname: Silverstein – volume: 63 start-page: 599 year: 1992 end-page: 602 ident: bib33 article-title: Oxygenation-deoxygenation cycle of erythrocytes modulates submicron cell membrane fluctuations publication-title: Biophys. J. contributor: fullname: Korenstein – volume: 94 start-page: 5045 year: 1997 end-page: 5049 ident: bib34 article-title: Cell membrane fluctuations are regulated by medium macroviscosity: evidence for a metabolic driving force publication-title: Proc. Natl. Acad. Sci. U. S. A. contributor: fullname: Yedgar – volume: 179 start-page: 601 year: 1994 end-page: 608 ident: bib6 article-title: Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes publication-title: J. Exp. Med. contributor: fullname: Miller – volume: 142 start-page: 1263 year: 1975 end-page: 1282 ident: bib15 article-title: Studies on the mechanism of phagocytosis I. Requirements for circunferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane publication-title: J. Exp. Med. contributor: fullname: Silverstein – volume: 60 start-page: 733 year: 1991 end-page: 737 ident: bib24 article-title: Membrane fluctuations in erythrocytes are linked to MgATP-dependent dynamic assembly of the membrane skeleton publication-title: Biophys. J. contributor: fullname: Korenstein – volume: 159 start-page: 881 year: 2002 end-page: 891 ident: bib3 article-title: Recruitment of the arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion publication-title: J. Cell Biol. contributor: fullname: Burridge – volume: 364 start-page: 639 year: 1993 end-page: 642 ident: bib5 article-title: Ruffles induced by salmonella and other stimuli direct macropinocytosis of bacteria publication-title: Nature contributor: fullname: Falkow – volume: 141 start-page: 1269 year: 1975 end-page: 1277 ident: bib14 article-title: Characterization of the macrophage receptor for complement and demonstration of its functional dependence from the receptor for the Fc portion of immunoglobulin G publication-title: J. Exp. Med. contributor: fullname: Silverstein – volume: 251 start-page: 7474 year: 1976 end-page: 7479 ident: bib35 article-title: Polymerization of publication-title: J. Biol. Chem. contributor: fullname: Korn – volume: 66 start-page: 627 year: 1998 end-page: 635 ident: bib18 article-title: Coiling phagocytosis discriminates between different spirochetes and is enhanced by phorbol myristate acetate and granulocytemacrophage colony-stimulating factor publication-title: Infect. Immun. contributor: fullname: Krause – volume: 5 start-page: 89 year: 1995 end-page: 93 ident: bib7 article-title: Phagocytosis by zippers and triggers publication-title: Trends Cell Biol. contributor: fullname: Baer – volume: 144 start-page: 788 year: 1976 end-page: 809 ident: bib16 article-title: Studies on the mechanism of phagocytosis II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes publication-title: J. Exp. Med. contributor: fullname: Silverstein – volume: 88 start-page: 161 year: 1998 end-page: 171 ident: bib30 article-title: publication-title: Exp. Parasitol. contributor: fullname: Mosser – volume: 19 start-page: 93 year: 1990 end-page: 99 ident: bib22 article-title: Local mechanical oscilations of the cell surface within range 0.2–30 Hz publication-title: Eur. Biophys. J. contributor: fullname: Smilgavichus – volume: 79 start-page: 4660 year: 1982 end-page: 4664 ident: bib36 article-title: Mobility of cytoplasmic and membrane-associated actin in living cells publication-title: Proc. Natl. Acad. Sci. U. S. A. contributor: fullname: Taylor – volume: 12 start-page: 112 year: 2002 end-page: 120 ident: bib1 article-title: The lamellipodium: where motility begins publication-title: Trends Cell Biol. contributor: fullname: Rottner – volume: 293 start-page: 207 year: 1991 end-page: 210 ident: bib23 article-title: Fast cell membrane displacements in B lymphocytes publication-title: FEBS contributor: fullname: Korenstein – volume: 13 start-page: R236 year: 2003 end-page: R238 ident: bib4 article-title: Lamellipodia protrusion: moving interactions of vinculin and arp2/3 publication-title: Curr. Biol. contributor: fullname: Chen – volume: 46 start-page: 669 year: 1977 end-page: 722 ident: bib21 article-title: Endocytosis publication-title: Annu. Rev. Biochem. contributor: fullname: Cohn – volume: 111 start-page: 2513 year: 1990 end-page: 2526 ident: bib20 article-title: Mechanics of fibroblast locomotion: quantitative analysis of forces and motions at the leading lamellas of fibroblasts publication-title: J. Cell Biol. contributor: fullname: Elson – volume: 81 start-page: 3414 year: 1984 end-page: 3418 ident: bib37 article-title: Diffusion of a small molecule in the cytoplasm of mammalian cells publication-title: Proc. Natl. Acad. Sci. U. S. A. contributor: fullname: Keith – volume: 17 start-page: 593 year: 1999 end-page: 623 ident: bib27 article-title: Mechanisms of phagocytosis in macrophages publication-title: Annu. Rev. Immunol. contributor: fullname: Underhill – volume: 63 start-page: 949 year: 1974 end-page: 969 ident: bib38 article-title: Pinocytosis in fibroblasts: quantitative studies in vitro publication-title: J. Cell Biol. contributor: fullname: Cohn – volume: 94 start-page: 4853 year: 1997 end-page: 4860 ident: bib10 article-title: Optical trapping and manipulation of neutral particles using lasers publication-title: Proc. Natl. Acad. Sci. U. S. A. contributor: fullname: Ashkin – volume: 11 start-page: 2999 year: 2000 end-page: 3012 ident: bib26 article-title: Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration publication-title: Mol. Biol. Cell contributor: fullname: Imhof – volume: 20 start-page: 825 year: 2002 end-page: 852 ident: bib28 article-title: Phagocytosis of microbes: complexity in action publication-title: Annu. Rev. Immunol. contributor: fullname: Ozinsky – volume: 61 start-page: 1553 year: 1993 end-page: 1558 ident: bib29 article-title: Comparison of receptors required for entry of publication-title: Infect. Immun. contributor: fullname: Belosevic – volume: 115 start-page: 2303 year: 2002 end-page: 2316 ident: bib32 article-title: Biogenesis of publication-title: J. Cell Sci. contributor: fullname: Antonine – volume: 293 start-page: 207 issue: 1–2 year: 1991 ident: 10.1016/j.yexcr.2004.09.002_bib23 article-title: Fast cell membrane displacements in B lymphocytes publication-title: FEBS doi: 10.1016/0014-5793(91)81188-E contributor: fullname: Mittelman – volume: 112 start-page: 453 year: 2003 ident: 10.1016/j.yexcr.2004.09.002_bib2 article-title: Cellular motility driven by assembly and disassembly of actin filaments publication-title: Cell doi: 10.1016/S0092-8674(03)00120-X contributor: fullname: Pollard – volume: 67 start-page: 051904 issue: 5 year: 2003 ident: 10.1016/j.yexcr.2004.09.002_bib9 article-title: Cell surface fluctuations studied with defocusing microscopy publication-title: Phys. Rev., E doi: 10.1103/PhysRevE.67.051904 contributor: fullname: Agero – volume: 11 start-page: 2999 year: 2000 ident: 10.1016/j.yexcr.2004.09.002_bib26 article-title: Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration publication-title: Mol. Biol. Cell doi: 10.1091/mbc.11.9.2999 contributor: fullname: Ballestrem – volume: 115 start-page: 2303 year: 2002 ident: 10.1016/j.yexcr.2004.09.002_bib32 article-title: Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites publication-title: J. Cell Sci. doi: 10.1242/jcs.115.11.2303 contributor: fullname: Courret – volume: 251 start-page: 7474 issue: 23 year: 1976 ident: 10.1016/j.yexcr.2004.09.002_bib35 article-title: Polymerization of Acanthamoeba actin publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(17)32873-9 contributor: fullname: Gordon – volume: 364 start-page: 639 year: 1993 ident: 10.1016/j.yexcr.2004.09.002_bib5 article-title: Ruffles induced by salmonella and other stimuli direct macropinocytosis of bacteria publication-title: Nature doi: 10.1038/364639a0 contributor: fullname: Francis – volume: 139 start-page: 323 year: 1974 ident: 10.1016/j.yexcr.2004.09.002_bib13 article-title: Segmental response of the macrophage plasma membrane to a phagocytic stimulus publication-title: J. Exp. Med. doi: 10.1084/jem.139.2.323 contributor: fullname: Griffin – volume: 111 start-page: 2513 issue: 6 year: 1990 ident: 10.1016/j.yexcr.2004.09.002_bib20 article-title: Mechanics of fibroblast locomotion: quantitative analysis of forces and motions at the leading lamellas of fibroblasts publication-title: J. Cell Biol. doi: 10.1083/jcb.111.6.2513 contributor: fullname: Felder – volume: 144 start-page: 788 year: 1976 ident: 10.1016/j.yexcr.2004.09.002_bib16 article-title: Studies on the mechanism of phagocytosis II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes publication-title: J. Exp. Med. doi: 10.1084/jem.144.3.788 contributor: fullname: Griffin – volume: 20 start-page: 825 year: 2002 ident: 10.1016/j.yexcr.2004.09.002_bib28 article-title: Phagocytosis of microbes: complexity in action publication-title: Annu. Rev. Immunol. doi: 10.1146/annurev.immunol.20.103001.114744 contributor: fullname: Underhill – volume: 112 start-page: 2993 year: 1999 ident: 10.1016/j.yexcr.2004.09.002_bib31 article-title: Leishmania species: models of intracellular parasitism publication-title: J. Cell Sci. doi: 10.1242/jcs.112.18.2993 contributor: fullname: Alexander – volume: 94 start-page: 5045 year: 1997 ident: 10.1016/j.yexcr.2004.09.002_bib34 article-title: Cell membrane fluctuations are regulated by medium macroviscosity: evidence for a metabolic driving force publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.94.10.5045 contributor: fullname: Tuvia – volume: 13 start-page: R236 year: 2003 ident: 10.1016/j.yexcr.2004.09.002_bib4 article-title: Lamellipodia protrusion: moving interactions of vinculin and arp2/3 publication-title: Curr. Biol. doi: 10.1016/S0960-9822(03)00160-X contributor: fullname: Craig – volume: 159 start-page: 881 issue: 5 year: 2002 ident: 10.1016/j.yexcr.2004.09.002_bib3 article-title: Recruitment of the arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion publication-title: J. Cell Biol. doi: 10.1083/jcb.200206043 contributor: fullname: DeMali – volume: 19 start-page: 93 year: 1990 ident: 10.1016/j.yexcr.2004.09.002_bib22 article-title: Local mechanical oscilations of the cell surface within range 0.2–30 Hz publication-title: Eur. Biophys. J. doi: 10.1007/BF00185092 contributor: fullname: Krol – volume: 5 start-page: 89 year: 1995 ident: 10.1016/j.yexcr.2004.09.002_bib7 article-title: Phagocytosis by zippers and triggers publication-title: Trends Cell Biol. doi: 10.1016/S0962-8924(00)88956-4 contributor: fullname: Swanson – volume: 60 start-page: 733 year: 1991 ident: 10.1016/j.yexcr.2004.09.002_bib24 article-title: Membrane fluctuations in erythrocytes are linked to MgATP-dependent dynamic assembly of the membrane skeleton publication-title: Biophys. J. doi: 10.1016/S0006-3495(91)82104-X contributor: fullname: Levin – volume: 88 start-page: 161 year: 1998 ident: 10.1016/j.yexcr.2004.09.002_bib30 article-title: Leishmania amazonensis: the phagocytosis of amastigotes by macrophages publication-title: Exp. Parasitol. doi: 10.1006/expr.1998.4232 contributor: fullname: Love – volume: 94 start-page: 4853 year: 1997 ident: 10.1016/j.yexcr.2004.09.002_bib10 article-title: Optical trapping and manipulation of neutral particles using lasers publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.94.10.4853 contributor: fullname: Ashkin – volume: 63 start-page: 949 year: 1974 ident: 10.1016/j.yexcr.2004.09.002_bib38 article-title: Pinocytosis in fibroblasts: quantitative studies in vitro publication-title: J. Cell Biol. doi: 10.1083/jcb.63.3.949 contributor: fullname: Steinman – volume: 5 start-page: 424 year: 1995 ident: 10.1016/j.yexcr.2004.09.002_bib8 article-title: Macropinocytosis publication-title: Trends Cell Biol doi: 10.1016/S0962-8924(00)89101-1 contributor: fullname: Swanson – volume: 66 start-page: 4331 issue: 9 year: 1998 ident: 10.1016/j.yexcr.2004.09.002_bib19 article-title: Coiling phagocytosis of tripanosomatids and fungal cells publication-title: Infect. Immun. doi: 10.1128/IAI.66.9.4331-4339.1998 contributor: fullname: Rittig – ident: 10.1016/j.yexcr.2004.09.002_bib11 – volume: 46 start-page: 669 year: 1977 ident: 10.1016/j.yexcr.2004.09.002_bib21 article-title: Endocytosis publication-title: Annu. Rev. Biochem. doi: 10.1146/annurev.bi.46.070177.003321 contributor: fullname: Silverstein – volume: 66 start-page: 627 issue: 2 year: 1998 ident: 10.1016/j.yexcr.2004.09.002_bib18 article-title: Coiling phagocytosis discriminates between different spirochetes and is enhanced by phorbol myristate acetate and granulocytemacrophage colony-stimulating factor publication-title: Infect. Immun. doi: 10.1128/IAI.66.2.627-635.1998 contributor: fullname: Rittig – volume: 63 start-page: 599 year: 1992 ident: 10.1016/j.yexcr.2004.09.002_bib33 article-title: Oxygenation-deoxygenation cycle of erythrocytes modulates submicron cell membrane fluctuations publication-title: Biophys. J. doi: 10.1016/S0006-3495(92)81625-9 contributor: fullname: Tuvia – volume: 179 start-page: 601 year: 1994 ident: 10.1016/j.yexcr.2004.09.002_bib6 article-title: Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes publication-title: J. Exp. Med. doi: 10.1084/jem.179.2.601 contributor: fullname: Alpuche-Aranda – volume: 79 start-page: 4660 year: 1982 ident: 10.1016/j.yexcr.2004.09.002_bib36 article-title: Mobility of cytoplasmic and membrane-associated actin in living cells publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.79.15.4660 contributor: fullname: Wang – volume: 12 start-page: 112 issue: 3 year: 2002 ident: 10.1016/j.yexcr.2004.09.002_bib1 article-title: The lamellipodium: where motility begins publication-title: Trends Cell Biol. doi: 10.1016/S0962-8924(01)02237-1 contributor: fullname: Small – volume: 61 start-page: 1553 issue: 4 year: 1993 ident: 10.1016/j.yexcr.2004.09.002_bib29 article-title: Comparison of receptors required for entry of Leishmania major amastigotes into macrophages publication-title: Infect. Immun. doi: 10.1128/iai.61.4.1553-1558.1993 contributor: fullname: Guy – volume: 36 start-page: 27 year: 1994 ident: 10.1016/j.yexcr.2004.09.002_bib17 article-title: Phagocytosis of the legionnaire's disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil publication-title: Cell doi: 10.1016/0092-8674(84)90070-9 contributor: fullname: Horwitz – volume: 17 start-page: 593 year: 1999 ident: 10.1016/j.yexcr.2004.09.002_bib27 article-title: Mechanisms of phagocytosis in macrophages publication-title: Annu. Rev. Immunol. doi: 10.1146/annurev.immunol.17.1.593 contributor: fullname: Aderem – volume: 81 start-page: 3414 year: 1984 ident: 10.1016/j.yexcr.2004.09.002_bib37 article-title: Diffusion of a small molecule in the cytoplasm of mammalian cells publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.81.11.3414 contributor: fullname: Mastro – volume: 113 start-page: 3329 year: 2000 ident: 10.1016/j.yexcr.2004.09.002_bib12 article-title: Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging publication-title: J. Cell Sci. doi: 10.1242/jcs.113.18.3329 contributor: fullname: Araki – volume: 142 start-page: 1263 year: 1975 ident: 10.1016/j.yexcr.2004.09.002_bib15 article-title: Studies on the mechanism of phagocytosis I. Requirements for circunferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane publication-title: J. Exp. Med. doi: 10.1084/jem.142.5.1263 contributor: fullname: Griffin – volume: 157 start-page: 1071 issue: 6 year: 2002 ident: 10.1016/j.yexcr.2004.09.002_bib25 article-title: Phospholipids undergo hop diffusion in compartmentalized cell membrane publication-title: J. Cell Biol. doi: 10.1083/jcb.200202050 contributor: fullname: Fujiwara – volume: 141 start-page: 1269 year: 1975 ident: 10.1016/j.yexcr.2004.09.002_bib14 article-title: Characterization of the macrophage receptor for complement and demonstration of its functional dependence from the receptor for the Fc portion of immunoglobulin G publication-title: J. Exp. Med. doi: 10.1084/jem.141.6.1269 contributor: fullname: Griffin |
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| SubjectTerms | Animals Bone Marrow Cells - parasitology Bone Marrow Cells - physiology Cell Membrane - physiology Defocusing microscopy In Vitro Techniques Leishmania mexicana - pathogenicity Macrophages - parasitology Macrophages - physiology Membrane fluctuations Membrane motility Membrane ruffles Mice Mice, Inbred C57BL Microscopy, Video - methods Movement Phagocytosis Phagocytosis - physiology Thermodynamics |
| Title | Real-time measurements of membrane surface dynamics on macrophages and the phagocytosis of Leishmania parasites |
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