The association of thrombosis with thrombocytopenia syndrome with cerebral venous thrombosis

• Published in: The American journal of emergency medicine Vol. 53; pp. 269 - 270
• Main Authors: Spadaro, Anthony, Scott, Kevin R., Koyfman, Alex, Long, Brit
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2022; Elsevier Limited
• Subjects: Adenoviruses; Cerebral venous thrombosis; Coronaviruses; COVID-19 vaccines; Emergency medical care; Hematology; Humans; Immunization; Intracranial Thrombosis - complications; Intracranial Thrombosis - diagnostic imaging; Leukopenia; Neurosurgery; Patients; Pulmonary embolisms; Radiology; Thrombocytopenia; Thrombocytopenia - complications; Thromboembolism; Thrombosis; thrombosis with thrombocytopenia syndrome; TTS; Vaccine-induced thrombosis and thrombocytopenia; Veins & arteries; Venous Thrombosis - complications; Venous Thrombosis - diagnostic imaging; VITT; United States > US; TTS; Vaccine-induced thrombosis and thrombocytopenia; thrombosis with thrombocytopenia syndrome; VITT; Thrombosis; Cerebral venous thrombosis
• ISSN: 0735-6757; 1532-8171
• DOI: 10.1016/j.ajem.2021.04.074

[...]according to data reported by Janssen, eight cases of CVT or thrombosis with thrombocytopenia have been associated with the Ad26Cov2.S vaccine [4]. [...]from the studies discussed, all patients had positive PF-4 assays (if the assay was available). [...]as this is a rapidly evolving field, involvement of a multidisciplinary team is recommended to manage a patient with TTS, including hematology, and as discussed in our paper, neurology, neurosurgery, or interventional radiology depending on local practice.Acknowledgements AT, BL, KRS, and AK conceived the idea for this manuscript and contributed substantially to the writing and editing of the review.