Observation of laser-induced elastic waves in agar skin phantoms using a high-speed camera and a laser-beam-deflection probe

• Published in: Biomedical optics express Vol. 9; no. 4; pp. 1893 - 1905
• Main Authors: Laloš, Jernej, Gregorčič, Peter, Jezeršek, Matija
• Format: Journal Article
• Language: English
• Published: United States Optical Society of America 01.04.2018
• Subjects: (170.0110) Imaging systems; (040.1490) Cameras; (170.0170) Medical optics and biotechnology; (100.3008) Image recognition, algorithms and filters; (280.3375) Laser induced ultrasonics; (140.3500) Lasers, erbium
• ISSN: 2156-7085; 2156-7085
• DOI: 10.1364/BOE.9.001893

We present an optical study of elastic wave propagation inside skin phantoms consisting of agar gel as induced by an Er:YAG (wavelength of 2.94 μm) laser pulse. A laser-beam-deflection probe is used to measure ultrasonic propagation and a high-speed camera is used to record displacements in ablation-induced elastic transients. These measurements are further analyzed with a custom developed image recognition algorithm utilizing the methods of particle image velocimetry and spline interpolation to determine point trajectories, material displacement and strain during the passing of the transients. The results indicate that the ablation-induced elastic waves propagate with a velocity of 1 m/s and amplitudes of 0.1 mm. Compared to them, the measured velocities of ultrasonic waves are much higher, within the range of 1.42-1.51 km/s, while their amplitudes are three orders of magnitude smaller. This proves that the agar gel may be used as a rudimental skin and soft tissue substitute in biomedical research, since its polymeric structure reproduces adequate soft-solid properties and its transparency for visible light makes it convenient to study with optical instruments. The results presented provide an insight into the distribution of laser-induced elastic transients in soft tissue phantoms, while the experimental approach serves as a foundation for further research of laser-induced mechanical effects deeper in the tissue.