Novel inhibitors of the hepatitis C virus NS3 proteinase - Bennett, Frank; Liu, Yi-Tsung; Saksena, Anil K.; Arasappan, Ashok; Butkiewicz, Nancy; Dasmahapatra, Bimalendu; Pichardo, John S.; Njoroge, F. George; Patel, Naginbhai M.; Huang, Yuhua; Yang, Xiaozheng (Bioorganic & medicinal chemistry letters, 2005)
Keywords: Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral agents; Antiviral Agents - chemical synthesis; Antiviral Agents - pharmacology; Biological and medical sciences; Dimerization; Hepatitis; Hepatitis C - enzymology; Inhibitory Concentration 50; Medical sciences; Oxidation-Reduction; Pharmacology. Drug treatments; Proteinase; Pyridines - chemistry; Serine Proteinase Inhibitors - chemical synthesis; Serine Proteinase Inhibitors - pharmacology; Structure-Activity Relationship; Viral Nonstructural Proteins - antagonists & inhibitors; Hepatitis; Proteinase; Enzyme; Enzyme inhibitor; In vitro; Biological activity; Pyridine derivatives; Virus; Autoxidation; Peptidases; Hydrolases; Antiviral; Dimer; Silica gel; Flaviviridae; Chemical synthesis; Hepatitis C virus; Hepacivirus; Protease inhibitor