Determination of circulating blood volume by continuously monitoring hematocrit during hemodialysis
Dialysis-induced hypovolemia occurs because the rate of extracorporeal ultrafiltration exceeds the rate of refilling of the blood compartment. The purpose of this study was to evaluate a method for calculating circulating blood volume (BV) during hemodialysis (HD) from changes in hematocrit (Hct) sh...
Saved in:
Published in | Journal of the American Society of Nephrology Vol. 6; no. 2; pp. 214 - 219 |
---|---|
Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.08.1995
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Dialysis-induced hypovolemia occurs because the rate of extracorporeal ultrafiltration exceeds the rate of refilling of the blood compartment. The purpose of this study was to evaluate a method for calculating circulating blood volume (BV) during hemodialysis (HD) from changes in hematocrit (Hct) shortly (2 to 10 min) before and after ultrafiltration (UF) was abruptly stopped. Hct was monitored continuously during 93 HD treatment sessions in 16 patients by an optical technique and at selected times by centrifugation of blood samples. Total plasma protein and albumin concentrations were also measured at selected times. Continuously monitored Hct correlated with Hct determined by centrifugation (R = 0.89, N = 579). Relative changes in BV determined by continuously monitored Hct were not different from those determined by total plasma protein concentration (P = 0.05; N = 273). Calculated BV at the start of dialysis (4.1 +/- 1.3 L) was not different (P = 0.18, N = 12) from that derived anthropometrically from the patient's dry weight (4.6 +/- 0.8 L), and calculated BV when UF was stopped was 3.2 +/- 0.5 L (46 +/- 7 ml/kg body wt). These latter estimates of BV are consistent with those determined previously by dilution techniques in HD patients. It was concluded that (1) relative changes in BV assessed by continuously monitored Hct were unbiased and (2) BV can be determined noninvasively during HD by continuously monitoring Hct and temporarily stopping UF. |
---|---|
AbstractList | Dialysis-induced hypovolemia occurs because the rate of extracorporeal ultrafiltration exceeds the rate of refilling of the blood compartment. The purpose of this study was to evaluate a method for calculating circulating blood volume (BV) during hemodialysis (HD) from changes in hematocrit (Hct) shortly (2 to 10 min) before and after ultrafiltration (UF) was abruptly stopped. Hct was monitored continuously during 93 HD treatment sessions in 16 patients by an optical technique and at selected times by centrifugation of blood samples. Total plasma protein and albumin concentrations were also measured at selected times. Continuously monitored Hct correlated with Hct determined by centrifugation (R = 0.89, N = 579). Relative changes in BV determined by continuously monitored Hct were not different from those determined by total plasma protein concentration (P = 0.05; N = 273). Calculated BV at the start of dialysis (4.1 +/- 1.3 L) was not different (P = 0.18, N = 12) from that derived anthropometrically from the patient's dry weight (4.6 +/- 0.8 L), and calculated BV when UF was stopped was 3.2 +/- 0.5 L (46 +/- 7 ml/kg body wt). These latter estimates of BV are consistent with those determined previously by dilution techniques in HD patients. It was concluded that (1) relative changes in BV assessed by continuously monitored Hct were unbiased and (2) BV can be determined noninvasively during HD by continuously monitoring Hct and temporarily stopping UF. |
Author | Harris, D H Steuer, R R Leypoldt, J K Conis, J M Cheung, A K |
Author_xml | – sequence: 1 givenname: J K surname: Leypoldt fullname: Leypoldt, J K organization: VA Medical Center, Salt Lake City, UT 84148, USA – sequence: 2 givenname: A K surname: Cheung fullname: Cheung, A K – sequence: 3 givenname: R R surname: Steuer fullname: Steuer, R R – sequence: 4 givenname: D H surname: Harris fullname: Harris, D H – sequence: 5 givenname: J M surname: Conis fullname: Conis, J M |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/7579087$$D View this record in MEDLINE/PubMed |
BookMark | eNo9kDtPwzAUhT0UlbawsCN5YkAK2I4f8ViVp1TBwGONHMcBI8cudlIp_56UFqarc_Tp6Oqbg4kP3gBwhtEV5gW-VslfbTkhmE7ADCPKM85FfgzmKX0hhBkRYgqmggmJCjED-sZ0JrbWq84GD0MDtY26d2P0H7ByIdRwG1zfGlgNUAc_9n3okxtgG7ztQtxxn6ZVXdDRdrDu_5pQW-WGZNMJOGqUS-b0cBfg7e72dfWQrZ_vH1fLdabzgnYZRUyZHOmmkJIzoyrRKKw4rzBvqppyxQiTBUMSac4apSThJCe80IRiLjHNF-Biv7uJ4bs3qStbm7RxTnkzvlwKwRFlXI7g5R7UMaQUTVNuom1VHEqMyp3FcvnyVL7_Whzh88NqX7Wm_kcPCvMfsBNzTg |
CitedBy_id | crossref_primary_10_1111_j_1476_4431_2005_00138_x crossref_primary_10_5301_ijao_5000167 crossref_primary_10_1081_JDI_100108193 crossref_primary_10_1111_j_1440_1797_1998_tb00364_x crossref_primary_10_1161_HYPERTENSIONAHA_110_154815 crossref_primary_10_1007_s11560_021_00520_3 crossref_primary_10_1046_j_1525_1594_1998_06036_x crossref_primary_10_3382_ps_pex363 crossref_primary_10_1097_MAT_0000000000000057 crossref_primary_10_1161_CIRCULATIONAHA_109_933275 crossref_primary_10_1111_j_1774_9987_2005_00235_x crossref_primary_10_1007_s00467_014_2986_1 crossref_primary_10_1111_hdi_12375 crossref_primary_10_1093_ndt_gfg590 crossref_primary_10_1007_s10439_016_1711_6 crossref_primary_10_1093_ndt_gfq016 crossref_primary_10_1117_1_3625283 crossref_primary_10_1111_hdi_13104 crossref_primary_10_1053_ajkd_2002_36894 crossref_primary_10_1007_BF02480778 crossref_primary_10_5301_ijao_5000414 crossref_primary_10_1097_MAT_0000000000000086 crossref_primary_10_1089_scd_1_1998_7_493 crossref_primary_10_1111_aor_12628 crossref_primary_10_1046_j_1523_1755_2000_07418_x crossref_primary_10_1016_j_jacc_2013_05_027 crossref_primary_10_1161_JAHA_122_028500 crossref_primary_10_1016_j_cardfail_2016_04_005 crossref_primary_10_1007_s00467_008_0985_9 crossref_primary_10_1007_BF02479977 crossref_primary_10_1046_j_1525_139X_1999_99011_x crossref_primary_10_1053_j_ajkd_2014_07_003 crossref_primary_10_1038_sj_ki_5000266 crossref_primary_10_1007_BF02479890 crossref_primary_10_1117_1_3233652 crossref_primary_10_1111_j_1525_139X_2010_00742_x crossref_primary_10_1016_j_aucc_2023_11_005 crossref_primary_10_1053_ajkd_2001_28090 crossref_primary_10_1053_ajkd_2001_28093 crossref_primary_10_1186_s12872_017_0669_0 crossref_primary_10_1007_s11255_016_1473_y crossref_primary_10_1111_j_1525_139X_2004_17112_x crossref_primary_10_1371_journal_pone_0220764 crossref_primary_10_1016_j_cjca_2013_12_005 crossref_primary_10_1161_HYPERTENSIONAHA_109_143974 crossref_primary_10_1299_jbse_23_00002 crossref_primary_10_1097_00041552_200311000_00010 crossref_primary_10_1053_j_ajkd_2007_10_036 crossref_primary_10_2215_CJN_04190412 crossref_primary_10_3390_jcm11061521 |
ContentType | Journal Article |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1681/asn.v62214 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EndPage | 219 |
ExternalDocumentID | 10_1681_ASN_V62214 7579087 |
Genre | Research Support, U.S. Gov't, Non-P.H.S Clinical Trial Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | --- .55 .GJ 0R~ 18M 29L 2WC 34G 39C 53G 5GY 5RE 5VS 6PF AAQQT AAUIN AAWTL ABJNI ABOCM ACGFO ACLDA ADBBV AENEX AFEXH AFFNX AHOMT ALMA_UNASSIGNED_HOLDINGS BAWUL BTFSW CGR CS3 CUY CVF DIK DU5 E3Z EBS ECM EIF EJD ERAAH F5P GX1 H13 HYE HZ~ K-O KQ8 NPM O9- OK1 OVD P0W P2P RHF RHI RPM TEORI TNP TR2 W8F X7M XVB YFH ZGI AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c384t-405ae30cf89965eab7fa1a66b16fbd46a525985090c65faa92623268c24169143 |
ISSN | 1046-6673 |
IngestDate | Fri Aug 16 12:12:57 EDT 2024 Fri Aug 23 00:39:52 EDT 2024 Wed Oct 16 00:42:52 EDT 2024 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c384t-405ae30cf89965eab7fa1a66b16fbd46a525985090c65faa92623268c24169143 |
Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
OpenAccessLink | https://jasn.asnjournals.org/content/jnephrol/6/2/214.full.pdf |
PMID | 7579087 |
PQID | 77604569 |
PQPubID | 23479 |
PageCount | 6 |
ParticipantIDs | proquest_miscellaneous_77604569 crossref_primary_10_1681_ASN_V62214 pubmed_primary_7579087 |
PublicationCentury | 1900 |
PublicationDate | 1995-08-01 |
PublicationDateYYYYMMDD | 1995-08-01 |
PublicationDate_xml | – month: 08 year: 1995 text: 1995-08-01 day: 01 |
PublicationDecade | 1990 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | Journal of the American Society of Nephrology |
PublicationTitleAlternate | J Am Soc Nephrol |
PublicationYear | 1995 |
SSID | ssj0015277 |
Score | 1.7963978 |
Snippet | Dialysis-induced hypovolemia occurs because the rate of extracorporeal ultrafiltration exceeds the rate of refilling of the blood compartment. The purpose of... |
SourceID | proquest crossref pubmed |
SourceType | Aggregation Database Index Database |
StartPage | 214 |
SubjectTerms | Blood Volume - physiology Female Hematocrit - methods Humans Male Monitoring, Physiologic Renal Dialysis |
Title | Determination of circulating blood volume by continuously monitoring hematocrit during hemodialysis |
URI | https://www.ncbi.nlm.nih.gov/pubmed/7579087 https://search.proquest.com/docview/77604569 |
Volume | 6 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9NAEF2FIiEuFS1UBEq7Etwql8TZD_sY9SuqaC-0KDdrdr0WlYpdRc4hPfDbO-td2xtKpcLFSlYa29l5Gb9Zv5kl5EsRs5xPGEQGPR4xI9MIOECk09TgN62EsPXOF5dids3O53w-GPwOq0tqdajv_1pX8j9exTH0q62S_QfPdifFAfyM_sUjehiPz_LxcatlaWmfvlnoZj8uzP8bSfqBiz6WZFpR-k25xEz_dnXwq_krN9q7pmtrhcGjbmsWcaSy9SS2WckT5DUoSCk75addfDAIjrWV-m9mdVfd5u6VR7-oevTT-DAzDVZaa7P0ezH3QsYZLBauEcKxr6TIfdUe7yRybVzFNDyyO4yGgVcE-IrXgigLnsc-pD4K9SKxoX76_fLwh4g7k7Cf9h_PuU59aPMetM7QNnO2L8jLWKbcSkLP5p1EyO74K103C3fzvr0t2n7tr7tOaJ7IUhq2cvWGbHpP0anDzBYZmHKbvLrwQoq3RK9Bh1YFDaBDG-hQN39UrWgIHdpDh_bQoQ46NITOO3J9enJ1NIv8fhuRniSsjpC7g5mMdIE5uOAGlCxgDEKosShUzgRwzJUTZJgjLXgBYFtNIvtPNLJAkSLx3iEbZVWa94SKFMYxSJbHuWZj26MwAVCqKEwCbGSSIfncTlp259qqZI_dMiT77XxmGPXsqywoDf7YTEphc5F0SHbcNHdnkVymo0R-eNYFPpLXPVp3yUa9WJpPSDJrtdcg4QESrIJL |
link.rule.ids | 315,786,790,27955,27956 |
linkProvider | Geneva Foundation for Medical Education and Research |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Determination+of+circulating+blood+volume+by+continuously+monitoring+hematocrit+during+hemodialysis&rft.jtitle=Journal+of+the+American+Society+of+Nephrology&rft.au=Leypoldt%2C+J+K&rft.au=Cheung%2C+A+K&rft.au=Steuer%2C+R+R&rft.au=Harris%2C+D+H&rft.date=1995-08-01&rft.issn=1046-6673&rft.volume=6&rft.issue=2&rft.spage=214&rft.epage=219&rft_id=info:doi/10.1681%2FASN.V62214&rft.externalDBID=n%2Fa&rft.externalDocID=10_1681_ASN_V62214 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1046-6673&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1046-6673&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1046-6673&client=summon |