Premedication with cyclooxygenase-2 inhibitor meloxicam reduced postoperative pain in patients after oral surgery

• Published in: International journal of oral and maxillofacial surgery Vol. 35; no. 7; pp. 613 - 617
• Main Authors: Aoki, T., Yamaguchi, H., Naito, H., Shiiki, K., Izawa, K., Ota, Y., Sakamoto, H., Kaneko, A.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.07.2006; Elsevier
• Subjects: Administration, Oral; Adult; Analysis of Variance; Anesthesia; Anesthesia, Local; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anti-Inflammatory Agents, Non-Steroidal - administration & dosage; Biological and medical sciences; Bones, joints and connective tissue. Antiinflammatory agents; Cyclooxygenase 2 Inhibitors - administration & dosage; cyclooxygenase-2 (COX-2) inhibitor; Dentistry; Double-Blind Method; Female; General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation; Humans; local anaesthesia; Male; Medical sciences; meloxicam; Molar, Third - surgery; oral surgery; Otorhinolaryngology. Stomatology; Pain Measurement; Pain, Postoperative - prevention & control; Pharmacology. Drug treatments; Phenylpropionates - therapeutic use; postoperative pain; Premedication; Prospective Studies; Thiazines - administration & dosage; Thiazoles - administration & dosage; Tooth Extraction; meloxicam; oral surgery; cyclooxygenase-2 (COX-2) inhibitor; local anaesthesia; postoperative pain; Human; Meloxicam; Postoperative; Prostaglandin-endoperoxide synthase; Oxicam derivatives; Enzyme; Stomatology; Enzyme inhibitor; Cyclooxygenase 2 inhibitor; Non steroidal antiinflammatory agent; Oral cavity; Analgesic; Pain; Treatment; Surgery; Anesthesia; Oxidoreductases; Premedication

The efficacy of the selective cyclooxygenase-2 (COX-2) inhibitor meloxicam for treatment of postoperative oral surgical pain was assessed in a randomized controlled trial. Patients undergoing unilateral mandibular 3rd molar extraction surgery were allocated to 3 groups, A, B and C. After oral premed...