miR-24-3p secreted as extracellular vesicle cargo by cardiomyocytes inhibits fibrosis in human cardiac microtissues - Senesi, Giorgia; Lodrini, Alessandra M; Mohammed, Shafeeq; Mosole, Simone; Hjortnaes, Jesper; Veltrop, Rogier J A; Kubat, Bela; Ceresa, Davide; Bolis, Sara; Raimondi, Andrea; Torre, Tiziano; Malatesta, Paolo; et al. (Cardiovascular research, 2025)
Keywords: Cell Transdifferentiation; Cells, Cultured; Cyclin D1 - genetics; Cyclin D1 - metabolism; Extracellular Vesicles - genetics; Extracellular Vesicles - metabolism; Extracellular Vesicles - pathology; Fibrosis; Humans; Induced Pluripotent Stem Cells - metabolism; Induced Pluripotent Stem Cells - pathology; MicroRNAs - genetics; MicroRNAs - metabolism; Myocytes, Cardiac - metabolism; Myocytes, Cardiac - pathology; Myofibroblasts - metabolism; Myofibroblasts - pathology; Original; Signal Transduction; Smad4 Protein - genetics; Smad4 Protein - metabolism; Transforming Growth Factor beta1 - metabolism; Myocardial infarction; Extracellular vesicles; Cardiac fibrosis; Cardiomyocytes; microRNA; Microtissues