Analysis of Gut Bacterial and Fungal Microbiota in Children with Autism Spectrum Disorder and Their Non-Autistic Siblings

• Published in: Nutrients Vol. 16; no. 17; p. 3004
• Main Authors: Retuerto, Mauricio, Al-Shakhshir, Hilmi, Herrada, Janet, McCormick, Thomas S., Ghannoum, Mahmoud A.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 05.09.2024
• Subjects: Animals; anxiety; autism; Autism Spectrum Disorder - microbiology; Autistic children; Azospirillum; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; bacteriome; Bacteroides fragilis; Behavior; biofilm; Biofilms; Candida albicans; Candida albicans - isolation & purification; Child; Child, Preschool; Consent; Cyanobacteria; Delftia acidovorans; Disease; dysbiosis; Dysbiosis - microbiology; Feces - microbiology; Female; fungi; Gastrointestinal Microbiome; Genetic testing; genus; Humans; inflammation; intestinal microorganisms; intestines; Male; Mice; Microbiota; multivariate analysis; Mycobiome; odds ratio; oral gavage; pathophysiology; Permeability; Prevotella; Probiotics; Questionnaires; Siblings; species; United States > US; probiotic; autism spectrum disorder (ASD); microbiome; regression analysis

Autism Spectrum Disorder (ASD) is a multifactorial disorder involving genetic and environmental factors leading to pathophysiologic symptoms and comorbidities including neurodevelopmental disorders, anxiety, immune dysregulation, and gastrointestinal (GI) abnormalities. Abnormal intestinal permeabil...