Adipose mesenchymal stem cell-derived exosomes stimulated by hydrogen peroxide enhanced skin flap recovery in ischemia-reperfusion injury

• Published in: Biochemical and biophysical research communications Vol. 500; no. 2; pp. 310 - 317
• Main Authors: Bai, Yun, Han, Yu-di, Yan, Xin-long, Ren, Jing, Zeng, Quan, Li, Xiao-dong, Pei, Xue-tao, Han, Yan
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 02.06.2018
• Subjects: 60 APPLIED LIFE SCIENCES; Adipose-derived stem cells; ANGIOGENESIS; Exosomes; Hydrogen peroxide; INFLAMMATION; ISCHEMIA; Ischemia-reperfusion injury; Neovascularization; SKIN; Skin flap transplantation; STEM CELLS; Skin flap transplantation; Ischemia-reperfusion injury; Adipose-derived stem cells; Hydrogen peroxide; Neovascularization; Exosomes

Mesenchymal stem cell (MSC)-derived exosomes have been recognized as new candidates for the treatment of ischemic disease or injury and may be an alternative treatment for cell therapy. This aim of the study was to evaluate whether exosomes derived from adipose mesenchymal stem cell (ADSC) can prote...