Dynamic functional connectivity changes associated with dementia in Parkinson’s disease

• Published in: Brain (London, England : 1878) Vol. 142; no. 9; pp. 2860 - 2872
• Main Authors: Fiorenzato, Eleonora, Strafella, Antonio P, Kim, Jinhee, Schifano, Roberta, Weis, Luca, Antonini, Angelo, Biundo, Roberta
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.09.2019
• Subjects: Cluster Analysis; Cognitive Dysfunction - etiology; Cognitive Dysfunction - pathology; Connectome; Dementia - etiology; Dementia - pathology; Editor's Choice; Educational Status; Female; Humans; Magnetic Resonance Imaging - methods; Male; Middle Aged; Neuroimaging - methods; Neuropsychological Tests; Original; Parkinson Disease - psychology; Severity of Illness Index; dynamic functional connectivity; dementia; mild cognitive impairment; Parkinson’s disease; neural networks

Dynamic functional connectivity captures temporal variations of functional connectivity during MRI acquisition and it may be a suitable method to detect cognitive changes in Parkinson’s disease. In this study, we evaluated 118 patients with Parkinson’s disease matched for age, sex and education with...