Unraveling the Role of MicroRNAs in Mycobacterium tuberculosis Infection and Disease: Advances and Pitfalls

• Published in: Infection and immunity Vol. 88; no. 3
• Main Authors: Ruiz-Tagle, Cinthya, Naves, Rodrigo, Balcells, María Elvira
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 20.02.2020
• Subjects: Animals; Biomarkers - metabolism; Gene Expression; Humans; Latent Tuberculosis - genetics; Latent Tuberculosis - immunology; Macrophages - immunology; Microbial Viability; MicroRNAs - genetics; MicroRNAs - metabolism; Minireview; Mycobacterium tuberculosis - pathogenicity; Mycobacterium tuberculosis - physiology; Signal Transduction - immunology; Tuberculosis - genetics; Tuberculosis - immunology; miRNA; infection; disease; Mycobacterium tuberculosis; biomarker; tuberculosis

Tuberculosis (TB) is an infectious disease of extremely high epidemiological burden worldwide that is easily acquired through the inhalation of infected respiratory droplets. The complex pathogenesis of this infection spans from subjects never developing this disease despite intense exposure, to oth...