Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients

• Published in: Journal of visualized experiments no. 137
• Main Authors: Carvalho, Fabiana, Brietzke, Aline Patrícia, Gasparin, Assunta, dos Santos, Franciele Pereira, Vercelino, Rafael, Ballester, Rafael Firmino, Sanches, Paulo Roberto Stefani, da Silva Jr, Danton Pereira, Torres, Iraci L. S., Fregni, Felipe, Caumo, Wolnei
• Format: Journal Article
• Language: English
• Published: United States MyJove Corporation 14.07.2018
• Subjects: adverse effects; cerebral cortex; computer software; electrodes; Medicine; membrane potential; monitoring; neurons; pain; patients; physical therapy; travel
• DOI: 10.3791/57614
• ISSN: 1940-087X

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation (NIBS) method, which modulates the membrane potential of neurons in the cerebral cortex by a low-intensity direct current. tDCS is a low-cost technique with minimal adverse effects and easy application. This neurostimulation method has a promising future to improve pain therapy, treatment of neuropsychiatric disorders, and physical rehabilitation. Current studies demonstrate the benefits of using tDCS over consecutive multiple sessions. However, the daily displacement to the specialized centers, travel costs, and disruptions to daily activities are some of the difficulties faced by patients. Thus, to be more comfortable, easy-to-use, and not disrupt daily commitments, a home-based tDCS was designed. Therefore, the objective of this study was to evaluate the feasibility of a portable tDCS device for home use in healthy subjects and fibromyalgia patients. Despite increased tDCS use and a reasonably large body of research on the effects across a range of clinical conditions, there is a limited amount of research on developing secure devices that guarantee the dose and contain a block system to avoid excessive use. Therefore, we used a tDCS device with a security system to permit daily use for 20 minutes with a minimal interval of 12 hours between sessions. A programmer preconfigures the equipment, which has a neoprene cap that allows the electrode positions in any assembly, according to individualized protocols for treatments or research. After, researchers can assess the effectiveness of treatment, and its adherence using information kept in the device software. Results suggest that the device is feasible for home use, with proper monitoring of adherence and contact impedance. There were reports of a few adverse effects, which do not differ from those reported in the literature in studies with the treatment under direct supervision.