Evidence that distinct human primary motor cortex circuits control discrete and rhythmic movements

• Published in: The Journal of physiology Vol. 598; no. 6; pp. 1235 - 1251
• Main Authors: Wiegel, Patrick, Kurz, Alexander, Leukel, Christian
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.03.2020
• Subjects: Circuits; Cortex (motor); corticospinal; discrete; Electromyography; Excitability; Humans; Magnetic fields; Motor Cortex - physiology; Motor task performance; Movement; Neural networks; Peripheral nerves; Pyramidal tracts; rhythmic; Rhythms; supragranular and infragranular layers; TMS; Transcranial Magnetic Stimulation; Wrist; discrete; TMS; M1; rhythmic; corticospinal; supragranular and infragranular layers

Key points Discrete and rhythmic dynamics are inherent components of (human) movements. We provide evidence that distinct human motor cortex circuits contribute to discrete and rhythmic movements. Excitability of supragranular layer circuits of the human motor cortex was higher during discrete movem...