Fetal growth in aneuploid conditions
Fetal growth failure is a significant clinical problem. Although aneuploid conditions account for only a few cases of intrauterine growth retardation, the clinical importance of these conditions is profound. Recognition of aneuploidy demands a high index of suspicion from the clinician and some know...
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Published in | Clinical obstetrics and gynecology Vol. 35; no. 1; p. 119 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
01.03.1992
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Subjects | |
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Abstract | Fetal growth failure is a significant clinical problem. Although aneuploid conditions account for only a few cases of intrauterine growth retardation, the clinical importance of these conditions is profound. Recognition of aneuploidy demands a high index of suspicion from the clinician and some knowledge of the growth patterns associated with these syndromes (Table 3). Symmetric growth retardation as a clinically recognizable entity probably does not exist. However, variations in the growth patterns in different aneuploidies may add important diagnostic clues to the evaluation of the growth-retarded fetus. In addition a better understanding of these patterns and their regulation may provide insight into the mechanisms, not only of abnormal, but perhaps more importantly, of normal fetal growth and development. |
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AbstractList | Fetal growth failure is a significant clinical problem. Although aneuploid conditions account for only a few cases of intrauterine growth retardation, the clinical importance of these conditions is profound. Recognition of aneuploidy demands a high index of suspicion from the clinician and some knowledge of the growth patterns associated with these syndromes (Table 3). Symmetric growth retardation as a clinically recognizable entity probably does not exist. However, variations in the growth patterns in different aneuploidies may add important diagnostic clues to the evaluation of the growth-retarded fetus. In addition a better understanding of these patterns and their regulation may provide insight into the mechanisms, not only of abnormal, but perhaps more importantly, of normal fetal growth and development. |
Author | Droste, S |
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SubjectTerms | Aneuploidy Chromosomes, Human, Pair 13 Chromosomes, Human, Pair 18 Down Syndrome - physiopathology Embryonic and Fetal Development - physiology Humans Trisomy |
Title | Fetal growth in aneuploid conditions |
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