Chronic eosinophilic leukemia presenting with autoimmune hemolytic anemia and erythrophagocytosis by eosinophils

• Published in: American journal of hematology Vol. 81; no. 6; pp. 458 - 461
• Main Authors: Kuk, J.S., MacEachern, J.A., Soamboonsrup, P., McFarlane, A., Benger, A., Patterson, W., Yang, L., Trus, M.R.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2006; Wiley-Liss
• Subjects: Aged; anemia; Anemia, Hemolytic, Autoimmune - blood; Anemia, Hemolytic, Autoimmune - complications; Anemia, Hemolytic, Autoimmune - pathology; Anemias. Hemoglobinopathies; Biological and medical sciences; Bone Marrow - pathology; Diseases of red blood cells; Eosinophils - pathology; Erythrocytes - pathology; erythrophagocytosis; Glycoproteins - metabolism; Hematologic and hematopoietic diseases; hemolytic; Humans; hypereosinophilia; Hypereosinophilic Syndrome - blood; Hypereosinophilic Syndrome - complications; Hypereosinophilic Syndrome - pathology; leukemia; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Leukocyte Count; Lymphoma, Non-Hodgkin - blood; Lymphoma, Non-Hodgkin - pathology; Lysophospholipase - metabolism; Male; Medical sciences; Myelopoiesis; Neoplasms, Second Primary - blood; Neoplasms, Second Primary - complications; Neoplasms, Second Primary - pathology; Phagocytosis; Autoimmunity; Immunopathology; leukemia; Eosinophilic leukemia; Hematology; Granulocyte; Malignant hemopathy; Eosinophil; Erythrophagocytosis; anemia; Myeloproliferative syndrome; Chronic; Hemolytic anemia; Autoimmune hemolytic anemia; hypereosinophilia; hemolytic

Eosinophils function primarily as secretory cells and phagocytosis by eosinophils is rarely seen. We describe a case of chronic eosinophilic leukemia (CEL) in a 72‐year‐old male with a history of previously treated non‐Hodgkin's lymphoma (NHL) presenting with erythrophagocytosis by eosinophils...