Vecuronium infusions for prolonged muscle relaxation in the intensive care unit

• Published in: Critical care medicine Vol. 17; no. 12; p. 1297
• Main Authors: Darrah, W C, Johnston, J R, Mirakhur, R K
• Format: Journal Article
• Language: English
• Published: United States 01.12.1989
• Subjects: Adult; Aged; Craniocerebral Trauma - complications; Craniocerebral Trauma - therapy; Critical Care; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Muscle Contraction - drug effects; Respiration, Artificial; Respiratory Insufficiency - etiology; Respiratory Insufficiency - therapy; Vecuronium Bromide - administration & dosage

Neuromuscular blockade by vecuronium infusion is described in 13 patients requiring ventilation in an ICU for periods of 15 to 68 h. A loading dose of vecuronium (0.1 mg/kg) was given, followed by continuous infusion adjusted to maintain approximately 90% block as assessed by the presence of one res...