An automated chromogenic peptide substrate assay for coagulation factor XII

• Published in: Blood coagulation & fibrinolysis Vol. 9; no. 2; p. 183
• Main Authors: Jones, D W, Gallimore, M J, Winter, M
• Format: Journal Article
• Language: English
• Published: England 01.01.1998
• Subjects: Autoanalysis - methods; Blood Donors; Case-Control Studies; Chromogenic Compounds; Factor XII - analysis; Humans; Linear Models; Lupus Coagulation Inhibitor - blood; Thrombophlebitis - blood

We have developed an automated chromogenic peptide substrate assay for factor XII (FXIIcs) on a Cobas Mira S Plus clinical chemistry analyser using a new commercially available kit. This was used to determine factor XII (FXII) levels in plasma samples from 320 blood donors, 206 patients with a histo...