Administration of Spermidine and Eugenol Demonstrates Anti-Tumorigenic Efficacy on Metastatic SW620 and Primary Caco-2 Colorectal Cancer Spheroids - Dilloo, Silvia; Whittaker, Anne; Chang, Xinyue; D’Amen, Eros; Spisni, Enzo; Hrelia, Silvana; Angeloni, Cristina; Malaguti, Marco; Dinelli, Giovanni; Truzzi, Francesca (International journal of molecular sciences, 2024)
Keywords: Antineoplastic Agents - pharmacology; Apoptosis; Apoptosis - drug effects; Autophagy; Caco-2 Cells; Cancer therapies; Care and treatment; Cell cycle; Cell Movement - drug effects; Cell Proliferation - drug effects; Colorectal cancer; Colorectal Neoplasms - drug therapy; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Cytotoxicity; Development and progression; Drug dosages; Eugenol; Eugenol - pharmacology; Eugenol - therapeutic use; Health aspects; Human Development Index; Humans; Kinases; Medical research; Metastasis; Natural products; Oils & fats; Physiological aspects; Polyamines; Spermidine - pharmacology; Spheroids; Spheroids, Cellular - drug effects; Tumors; Italy; spermidine; Caco-2 spheroids; anti-tumorigenic efficacy; migration; SW620; apoptosis; eugenol; co-culture intestinal equivalents