Oleic Acid Protects Against Insulin Resistance by Regulating the Genes Related to the PI3K Signaling Pathway

• Published in: Journal of clinical medicine Vol. 9; no. 8; p. 2615
• Main Authors: López-Gómez, Carlos, Santiago-Fernández, Concepción, García-Serrano, Sara, García-Escobar, Eva, Gutiérrez-Repiso, Carolina, Rodríguez-Díaz, Cristina, Ho-Plágaro, Ailec, Martín-Reyes, Flores, Garrido-Sánchez, Lourdes, Valdés, Sergio, Rodríguez-Cañete, Alberto, Rodríguez-Pacheco, Francisca, García-Fuentes, Eduardo
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 12.08.2020; MDPI
• Subjects: Adipocytes; Binding sites; Biobanks; Biopsy; Body fat; Clinical medicine; Fatty acids; Gastrointestinal surgery; Gene expression; Glucose; Hernias; Insulin resistance; Kinases; Laparoscopy; Lipids; Metabolism; Musculoskeletal system; Obesity; Phosphorylation; Proteins; Statistical analysis; United States > US; Germany

Background: The effects of different types of fatty acids on the gene expression of key players in the IRS1/PI3K signaling pathway have been poorly studied. Material and Methods: We analyzed IRS1, p85α, and p110β mRNA expression and the fatty acid composition of phospholipids in visceral adipose tis...