Long-term stability of intracortical recordings using perforated and arrayed Parylene sheath electrodes

• Published in: Journal of neural engineering Vol. 13; no. 6; pp. 66020 - 66036
• Main Authors: Hara, Seth A, Kim, Brian J, Kuo, Jonathan T W, Lee, Curtis D, Meng, Ellis, Pikov, Victor
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 01.12.2016
• Subjects: Animals; Axons; brain-machine interfaces; Caveolin 1 - biosynthesis; Caveolin 1 - genetics; Cell Proliferation; Cerebral Cortex - cytology; Cerebral Cortex - physiology; chronic implants; Coated Materials, Biocompatible - chemistry; dendrite sprouting; Dendrites; Electrochemical Techniques; Electrocorticography - instrumentation; Electrodes, Implanted; Immunohistochemistry; intracortical electrode array; microelectrode array; neural interface; Neural Prostheses; Parylene; Platinum; Polymers - chemistry; Prosthesis Design; Rats; Signal-To-Noise Ratio; Xylenes - chemistry
• ISSN: 1741-2560; 1741-2552; 1741-2552
• DOI: 10.1088/1741-2560/13/6/066020

Objective. Acquisition of reliable and robust neural recordings with intracortical neural probes is a persistent challenge in the field of neuroprosthetics. We developed a multielectrode array technology to address chronic intracortical recording reliability and present in vivo recording results. Ap...