Enhanced Lung Cancer Detection Using a Combined Ratio of Antigen-Autoantibody Immune Complexes against CYFRA 21-1 and p53

• Published in: Cancers Vol. 16; no. 15; p. 2661
• Main Authors: Kim, Heyjin, Lee, Jin Kyung, Kim, Hye-Ryoun, Hong, Young Jun
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.08.2024
• Subjects: Antigen (tumor-associated); Antigen-antibody complexes; Antigens; Autoantibodies; autoantibody; Autoimmunity; biomarker; Biomarkers; Cancer; Cancer therapies; Cell cycle; CYFRA 21-1; Development and progression; Diagnosis; Disease; Ethylenediaminetetraacetic acid; Immune system; Lung cancer; Medical prognosis; Medical records; Mortality; Mutation; Oncology, Experimental; p53; p53 Protein; Plasma; Proteins; Sensitivity analysis; Tumor proteins; South Korea; lung cancer; autoantibody; biomarker; CYFRA 21-1; p53

The early detection of lung cancer (LC) improves patient outcomes, but current methods have limitations. Autoantibodies against tumor-associated antigens have potential as early biomarkers. This study evaluated the 9G test Cancer/Lung, measuring circulating complexes of two antigen-autoantibody immu...