Evaluation of biological monitoring markers using genomic and proteomic analysis for automobile emission inspectors and waste incinerating workers exposed to polycyclic aromatic hydrocarbons or 2,3,7,8,-tetracholrodedibenzo-p-dioxins

• Published in: Experimental & molecular medicine Vol. 36; no. 5; pp. 396 - 410
• Main Authors: Kim, Meyoung Kon, Oh, Sangnam, Lee, Ji Hye, Im, Hosub, Ryu, Yeon Mi, Oh, Eunha, Lee, Joohyun, Lee, Eunil, Sul, Donggeun
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 31.10.2004
• Subjects: Adult; Aged; Biomarkers - analysis; DNA Fragmentation; Environmental Monitoring - methods; Gene Expression Profiling; Genetic Markers; Genomics; Humans; Incineration; Middle Aged; Naphthols - urine; Occupational Exposure - analysis; Olea; Oligonucleotide Array Sequence Analysis; Polychlorinated Dibenzodioxins - analysis; Polychlorinated Dibenzodioxins - toxicity; Polycyclic Aromatic Hydrocarbons - analysis; Polycyclic Aromatic Hydrocarbons - toxicity; Proteomics; Pyrenes - analysis; Vehicle Emissions

In this study, we investigated the effects of PAHs and dioxin on mRNA and plasma protein expression using genomic and proteomic analysis for automobile emission inspectors and waste incineration workers. About 54 workers from automobile emission inspection offices, 31 workers from waste incinerating...