Nucleotide correlations that suggest tertiary interactions in the TV-replacement loop-containing mitochondrial tRNAs of the nematodes, Caenorhabditis elegans and Ascaris suum

• Published in: Nucleic acids research Vol. 22; no. 20; pp. 4300 - 4306
• Main Authors: Wolstenholme, D.R, Okimoto, R, Macfarlane, J.L
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 11.10.1994
• Subjects: Animals; Ascaris suum; Ascaris suum - genetics; Base Sequence; Caenorhabditis elegans; Caenorhabditis elegans - genetics; Cattle; DNA, Helminth - chemistry; DNA, Mitochondrial - chemistry; Hydrogen Bonding; mitochondria; molecular conformation; Molecular Sequence Data; Nematoda; Nucleic Acid Conformation; nucleotide sequences; protein secondary structure; protein tertiary structure; RNA, Helminth - chemistry; RNA, Transfer - chemistry; RNA, Transfer, Phe - chemistry; RNA, Transfer, Ser - chemistry; transfer RNA

In the predicted secondary structures of 20 of the 22 tRNAs encoded in mitochondrial DNA (mtDNA) molecules of the nematodes, Caenorhabditis elegans and Ascaris suum, the T pseudoridine C arm and variable loop are replaced with a loop of 6 to 12 nucleotides: the TV-replacement loop. From consideratio...