Noninvasive Imaging of the Foveal Avascular Zone with High-Speed, Phase-Variance Optical Coherence Tomography

• Published in: Investigative ophthalmology & visual science Vol. 53; no. 1; pp. 85 - 92
• Main Authors: Kim, Dae Yu, Fingler, Jeff, Zawadzki, Robert J., Park, Susanna S., Morse, Lawrence S., Schwartz, Daniel M., Fraser, Scott E., Werner, John S.
• Format: Journal Article
• Language: English
• Published: United States Association for Research in Vision and Ophthalmology, Inc 05.01.2012
• Subjects: Adult; Aged; Capillaries - pathology; Diabetic Retinopathy - diagnosis; Female; Fluorescein Angiography; Fourier Analysis; Fovea Centralis - blood supply; Fovea Centralis - pathology; Humans; Imaging, Three-Dimensional; Male; Microcirculation; Middle Aged; Retinal Vessels - pathology; Tomography, Optical Coherence

To demonstrate the application of phase-variance optical coherence tomography (pvOCT) for contrast agent-free in vivo imaging of volumetric retinal microcirculation in the human foveal region and for extraction of foveal avascular zone dimensions. A custom-built, high-speed Fourier-domain OCT retina...