Tissue-specific role of Nrf2 in the treatment of diabetic foot ulcers during hyperbaric oxygen therapy

• Published in: Free radical biology & medicine Vol. 138; pp. 53 - 62
• Main Authors: Dhamodharan, Umapathy, Karan, Amin, Sireesh, Dornadula, Vaishnavi, Alladi, Somasundar, Arumugam, Rajesh, Kesavan, Ramkumar, Kunka Mohanram
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2019

Hyperbaric oxygen (HBO) therapy is proven to be very successful for diabetic foot ulcer (DFU) treatment due to its antimicrobial effect, increased angiogenesis and enhanced collagen synthesis. The molecular mechanism underlying HBO therapy particularly the involvement of Nrf2 in the wound healing pr...