Customized multiplexing SNP panel for Korean-specific DNA phenotyping in forensic applications

• Published in: Genes & genomics Vol. 39; no. 7; pp. 723 - 732
• Main Authors: Lim, Seri, Youn, Jong Pil, Hong, Seungbeom, Choi, Dongho, Moon, Seohyun, Kim, Wook, Han, Myunsoo, Hwang, Seung Yong
• Format: Journal Article
• Language: English
• Published: Seoul The Genetics Society of Korea 01.07.2017; Springer Nature B.V; 한국유전학회
• Subjects: alleles; Animal Genetics and Genomics; Asians; Biomedical and Life Sciences; Deoxyribonucleic acid; DNA; Forensic science; Forensic sciences; Genetic markers; genetic similarity; high-throughput nucleotide sequencing; Human Genetics; humans; Korean Peninsula; Life Sciences; Microbial Genetics and Genomics; Minority & ethnic groups; Paternity; Paternity testing; phenotype; Phenotyping; Plant Genetics and Genomics; Polymorphism; Population genetics; Research Article; screening; Single-nucleotide polymorphism; 생물학; Korean Peninsula; Forensic DNA identification; Ion PGM; Massively parallel sequencing; Multiplexed SNP panel; Genomic variation

Due to the recent growth of the alien population in Korea, tracking the ethnic origin of human specimens has gained importance in genetic forensics. To address this issue, we developed a method to analyze single nucleotide polymorphisms (SNPs) based on next-generation sequencing (NGS) technology, wh...