Single Subject Classification of Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia Using Anatomical, Diffusion Tensor, and Resting-State Functional Magnetic Resonance Imaging

• Published in: Journal of Alzheimer's disease Vol. 62; no. 4; p. 1827
• Main Authors: Bouts, Mark J R J, Möller, Christiane, Hafkemeijer, Anne, van Swieten, John C, Dopper, Elise, van der Flier, Wiesje M, Vrenken, Hugo, Wink, Alle Meije, Pijnenburg, Yolande A L, Scheltens, Philip, Barkhof, Frederik, Schouten, Tijn M, de Vos, Frank, Feis, Rogier A, van der Grond, Jeroen, de Rooij, Mark, Rombouts, Serge A R B
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2018
• Subjects: behavioral variant frontotemporal dementia; functional MRI; differential diagnosis; Alzheimer’s disease; diffusion tensor imaging; classification; machine learning

Overlapping clinical symptoms often complicate differential diagnosis between patients with Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD). Magnetic resonance imaging (MRI) reveals disease specific structural and functional differences that aid in differentiatin...