Determinants of Intracerebral Hemorrhage Growth An Exploratory Analysis

• Published in: Stroke (1970) Vol. 38; no. 3; pp. 1072 - 1075
• Main Authors: Broderick, Joseph P., Diringer, Michael N., Hill, Michael D., Brun, Nikolai C., Mayer, Stephan A., Steiner, Thorsten, Skolnick, Brett E., Davis, Stephen M.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.03.2007
• Subjects: Biological and medical sciences; Cerebral Hemorrhage - diagnosis; Cerebral Hemorrhage - drug therapy; Cerebral Hemorrhage - physiopathology; Double-Blind Method; Drug toxicity and drugs side effects treatment; Factor VIIa - therapeutic use; Follow-Up Studies; Hematologic and hematopoietic diseases; Humans; Medical sciences; Models, Statistical; Multivariate Analysis; Neurology; Pharmacology. Drug treatments; Platelet diseases and coagulopathies; Recombinant Proteins - therapeutic use; Tomography, X-Ray Computed; Toxicity: nervous system and muscle; Vascular diseases and vascular malformations of the nervous system; Vascular disease; Stroke; Nervous system diseases; intracerebral hemorrhage ■ intraventricular hemorrhage ■ growth ■ recombinant activated factor VII ■ volume; Cerebral hemorrhage; Central nervous system disease; Cardiovascular disease; Cerebral ventricle; Cerebrovascular disease; Cerebral disorder; Growth factor; Factor VII
• ISSN: 0039-2499; 1524-4628; 1524-4628
• DOI: 10.1161/01.STR.0000258078.35316.30

Background and Purpose— We report an exploratory analysis from a randomized study of recombinant activated factor VII (rFVIIa) in patients with intracerebral hemorrhage (ICH) examining potential factors associated with hemorrhage growth. Methods— We explored the relationship between 5 different meas...