Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration - You, Baiyang; Liu, Yanbo; Chen, Jia; Huang, Xiao; Peng, Huihui; Liu, Zhaoya; Tang, Yixin; Zhang, Kai; Xu, Qian; Li, Xiaohui; Cheng, Guangjie; Shi, Ruizheng; et al. (Cardiovascular research, 2018)
Keywords: Animals; Apoptosis; Apoptosis Regulatory Proteins - metabolism; Cell Cycle Proteins - metabolism; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hemeproteins - metabolism; Hypertension, Pulmonary - enzymology; Hypertension, Pulmonary - etiology; Hypertension, Pulmonary - pathology; Hypochlorous Acid - metabolism; Hypoxia - complications; Hypoxia - enzymology; Male; Matrix Metalloproteinase 2 - metabolism; Matrix Metalloproteinase 9 - metabolism; Muscle, Smooth, Vascular - enzymology; Muscle, Smooth, Vascular - pathology; Myocytes, Smooth Muscle - enzymology; Myocytes, Smooth Muscle - pathology; NADPH Oxidase 4 - metabolism; NF-kappa B - metabolism; Peroxidases - metabolism; Pulmonary Artery - enzymology; Pulmonary Artery - pathology; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling; NF-κB; Hypoxia; Vascular peroxidase 1; Pulmonary vascular remodelling; Pulmonary artery smooth muscle cells