Clinical Pharmacokinetics and Drug‐Drug Interaction Potential for Coadministered SCY‐078, an Oral Fungicidal Glucan Synthase Inhibitor, and Tacrolimus - Wring, Stephen; Murphy, Gail; Atiee, George; Corr, Christy; Hyman, Michele; Willett, Michael; Angulo, David (Clinical pharmacology in drug development, 2019)
Keywords: Administration, Oral; Adult; antifungal; Antifungal Agents - adverse effects; Antifungal Agents - blood; Antifungal Agents - pharmacokinetics; Antifungal Agents - pharmacology; Drug dosages; drug interaction; Drug Interactions; Glucosyltransferases - antagonists & inhibitors; Glycosides - adverse effects; Glycosides - blood; Glycosides - pharmacokinetics; Glycosides - pharmacology; Humans; Immunosuppressive Agents - adverse effects; Immunosuppressive Agents - blood; Immunosuppressive Agents - pharmacokinetics; Immunosuppressive Agents - pharmacology; Male; Pharmacokinetics; Pharmacology; tacrolimus; Tacrolimus - adverse effects; Tacrolimus - blood; Tacrolimus - pharmacokinetics; Tacrolimus - pharmacology; Triterpenes - adverse effects; Triterpenes - blood; Triterpenes - pharmacokinetics; Triterpenes - pharmacology; pharmacokinetics; antifungal; drug interaction; tacrolimus; pharmacology