Subunit Antigen and Activity Levels of Blood Coagulation Factor XIII in Healthy Individuals: Relation to Sex, Age, Smoking, and Hypertension

• Published in: Arteriosclerosis, thrombosis, and vascular biology Vol. 19; no. 8; pp. 2012 - 2016
• Main Authors: Ariëns, R A.S, Kohler, H P, Mansfield, M W, Grant, P J
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA American Heart Association, Inc 01.08.1999; Hagerstown, MD Lippincott
• Subjects: Adult; Aged; Aged, 80 and over; Aging - blood; Antigens - blood; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Factor XIII - immunology; Female; Humans; Hypertension - blood; Hypertension - immunology; Male; Medical sciences; Middle Aged; Regression Analysis; Smoking - blood; Smoking - immunology; Transglutaminases - metabolism; Vascular disease; Human; Hypertension; Toxicology; Factor XIII; Atherosclerosis; Risk factor; Sex; Tobacco smoking; Cardiovascular disease; Age

Factor (F) XIII covalently cross-links and stabilizes the fibrin-clot. Recent evidence suggests a role for FXIII in atherothrombotic diseases, but no information is available regarding the association of FXIII with common risk factors. The aim of this study was to investigate the relationship of FXI...