Sports drug testing and the athletes' exposome
Similar to the general population, elite athletes are exposed to a complex set of environmental factors including chemicals and radiation and also biological and physical stressors, which constitute an exposome that is, unlike for the general population, subjected to specific scrutiny for athletes d...
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| Published in | Drug testing and analysis Vol. 13; no. 11-12; pp. 1814 - 1821 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.11.2021
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1942-7603 1942-7611 |
| DOI | 10.1002/dta.3187 |
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| Abstract | Similar to the general population, elite athletes are exposed to a complex set of environmental factors including chemicals and radiation and also biological and physical stressors, which constitute an exposome that is, unlike for the general population, subjected to specific scrutiny for athletes due to applicable antidoping regulations and associated (frequent) routine doping controls. Hence, investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, as a delicate balance is to be managed between the vital and continually evolving developments of sensitive analytical techniques on the one hand, and the risk of the athletes' exposome potentially causing adverse analytical findings on the other.
Investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, and a variety of challenges need to be taken into consideration. |
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| AbstractList | Similar to the general population, elite athletes are exposed to a complex set of environmental factors including chemicals and radiation and also biological and physical stressors, which constitute an exposome that is, unlike for the general population, subjected to specific scrutiny for athletes due to applicable antidoping regulations and associated (frequent) routine doping controls. Hence, investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, as a delicate balance is to be managed between the vital and continually evolving developments of sensitive analytical techniques on the one hand, and the risk of the athletes' exposome potentially causing adverse analytical findings on the other.
Investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, and a variety of challenges need to be taken into consideration. Similar to the general population, elite athletes are exposed to a complex set of environmental factors including chemicals and radiation and also biological and physical stressors, which constitute an exposome that is, unlike for the general population, subjected to specific scrutiny for athletes due to applicable antidoping regulations and associated (frequent) routine doping controls. Hence, investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, as a delicate balance is to be managed between the vital and continually evolving developments of sensitive analytical techniques on the one hand, and the risk of the athletes' exposome potentially causing adverse analytical findings on the other. |
| Author | Kuuranne, Tiia Fedoruk, Matthew Geyer, Hans Thevis, Mario |
| Author_xml | – sequence: 1 givenname: Mario orcidid: 0000-0002-1535-6451 surname: Thevis fullname: Thevis, Mario email: m.thevis@biochem.dshs-koeln.de organization: European Monitoring Center for Emerging Doping Agents – sequence: 2 givenname: Tiia surname: Kuuranne fullname: Kuuranne, Tiia organization: Centre Hospitalier Universitaire Vaudois and University of Lausanne – sequence: 3 givenname: Matthew orcidid: 0000-0002-9553-9476 surname: Fedoruk fullname: Fedoruk, Matthew organization: United States Anti‐Doping Agency (USADA) – sequence: 4 givenname: Hans surname: Geyer fullname: Geyer, Hans organization: European Monitoring Center for Emerging Doping Agents |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34694748$$D View this record in MEDLINE/PubMed |
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| Copyright | 2021 The Authors. published by John Wiley & Sons Ltd. 2021 The Authors. Drug Testing and Analysis published by John Wiley & Sons Ltd. |
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| Issue | 11-12 |
| Keywords | doping drug exposure adverse analytical finding sport contamination |
| Language | English |
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| References | 2013; 3 2021; 20 2013; 27 2018; 161 2002; 50 2019; 11 2019; 59 2016; 267 1977; 66 2020; 12 1994; 26 2020; 98 2013; 5 2017; 9 2014; 137 2020; 405 2012; 52 1985; 19 2021; 35 2020; 6 1979; 68 2021; 33 2000; 14 2000 1997; 10 2019; 26 2020; 9 2017; 34 1964; 145 2001; 15 1998; 96 2003; 84 2014; 6 1987; 13 2015; 1 2019; 7 1987; 11 2013; 47 2021; 42 2011 2010 1991; 31 1980; 22 2009 2020; 37 2011; 34 2011; 3 2007; 55 2009; 26 2011; 210 2018; 26 2016; 12 2016; 56 1994; 42 2009; 28 2021; 13 2015; 26 2009; 74 2004; 50 2021; 55 2006; 40 2015; 115 2021 2020 2019; 43 2021; 18 1986; 24 1975; 23 2019 2018 2017 2003; 27 2018; 96 2018; 52 2008; 43 2018; 10 2012; 4 2003; 20 2014; 33 2005; 14 |
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| SubjectTerms | adverse analytical finding Athletes contamination doping Doping in Sports - prevention & control Drug Contamination - prevention & control drug exposure Exposome Humans sport Sports Substance Abuse Detection - methods |
| Title | Sports drug testing and the athletes' exposome |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fdta.3187 https://www.ncbi.nlm.nih.gov/pubmed/34694748 |
| Volume | 13 |
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