Anion exchanger1 (AE1/SLC4A1) function is impaired in red blood cells from prediabetic subjects: Potential benefits of finger lime (Citrus australasica, Faustrime cultivar) juice extract - Remigante, Alessia; Spinelli, Sara; Gambardella, Lucrezia; Straface, Elisabetta; Cafeo, Giovanna; Russo, Marina; Caruso, Daniele; Dugo, Paola; Dossena, Silvia; Marino, Angela; Morabito, Rossana (Cell biochemistry and function, 2024)
Keywords: Adult; Anion exchange; Anion Exchange Protein 1, Erythrocyte - metabolism; anion exchanger 1 (SLC4A1); Anion exchanging; Antioxidants; Antioxidants - chemistry; Antioxidants - metabolism; Antioxidants - pharmacology; Bioactive compounds; Biological activity; Biomarkers; Cardiovascular diseases; Catalase; Cellular structure; Citrus - chemistry; Citrus australasica; Citrus fruits; Condition monitoring; Cultivars; Diabetes mellitus; Dietary supplements; Erythrocytes; Erythrocytes - drug effects; Erythrocytes - metabolism; Female; Fruit and Vegetable Juices - analysis; Functional foods & nutraceuticals; Glutathione; glycation; Glycosylation; Hemoglobin; Homeostasis; Humans; Hyperglycemia; Juices; Lipid peroxidation; Lipids; Male; Methemoglobin; Middle Aged; Molecular modelling; Oxidation; Oxidation resistance; Oxidative stress; Oxidative Stress - drug effects; Peroxidation; Plant Extracts - chemistry; Plant Extracts - pharmacology; Prediabetic State - drug therapy; Prediabetic State - metabolism; Prevention; red blood cells; Spectrin; Structure-function relationships; Superoxide dismutase; glycation; red blood cells; anion exchanger 1 (SLC4A1); hyperglycemia; oxidative stress