Differences in the placebo response in duloxetine and venlafaxine trials

• Published in: Acta psychiatrica Scandinavica Vol. 137; no. 6; pp. 472 - 480
• Main Authors: Breilmann, J., Furukawa, T. A., Becker, T., Koesters, M.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.06.2018
• Subjects: Antidepressants; Duloxetine; Mental depression; Meta-analysis; moderator variables; Placebo effect; Placebos; Venlafaxine; meta-analysis; placebo effect; antidepressants; moderator variables

Objective Our analysis aimed at comparing the placebo effect sizes from randomized controlled trials (RCTs) of two widely prescribed antidepressants, namely duloxetine and venlafaxine, and at analysing a potential influence of the investigated drugs on the placebo response. Method We conducted a com...