Retinal tears and rhegmatogenous retinal detachment after intravitreal injections: its prevalence and case reports

• Published in: Digital journal of ophthalmology Vol. 21; no. 1; pp. 8 - 7
• Main Authors: Karabag, Revan Yildirim, Parlak, Melih, Cetin, Gölgem, Yaman, Aylin, Osman Saatci, A
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Eye and Ear Infirmary 2015
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Eye Diseases - drug therapy; Female; Humans; Intravitreal Injections - adverse effects; Intravitreal Injections - statistics & numerical data; Male; Middle Aged; Ophthalmic Solutions - administration & dosage; Ophthalmic Solutions - adverse effects; Original; Postoperative Complications - etiology; Retinal Detachment - etiology; Retinal Perforations - etiology; Retrospective Studies; Young Adult
• ISSN: 1542-8958; 1542-8958
• DOI: 10.5693/djo.01.2014.07.001

To report the prevalence of postoperative retinal tear or rhegmatogenous retinal detachment secondary to intravitreal injections. Surgical and medical records of patients who received intravitreal injections at the practice of a single retina specialist from January 2004 to May 2013 and who were followed for at least 6 months were investigated retrospectively. During the study period, a total of 3,907 intravitreal injections were performed in 1,049 eyes of 784 patients (416 males [47%]). The mean number of injections per eye was 3.72 ± 3.43 (range, 1-22). The mean age of the participants was 67.03 ± 13.56 (range, 5-94 years). The mean follow-up time was 31.98 ± 22.86 months (range, 6-144 months). Retinal break or rhegmatogenous retinal detachment occurred in 3 injections of 3 eyes, yielding an overall prevalence of 0.077% per injection and 0.29% per eye. Retinal tear and rhegmatogenous detachment are rare complications of intravitreal injection. Precautions should be taken especially in patients having predisposing conditions, such as high myopia, or any other vitreoretinal disorders.