Survival, Growth, and Reproduction Responses in a Three‐Generation Exposure of the Zebrafish (Danio rerio) to Perfluorooctane Sulfonate

• Published in: Environmental toxicology and chemistry Vol. 43; no. 1; pp. 115 - 131
• Main Authors: Gust, Kurt A., Mylroie, J. Erik, Kimble, Ashley N., Wilbanks, Mitchell S., Steward, Catherine S. C., Chapman, Kacy A., Jensen, Kathleen M., Kennedy, Alan J., Krupa, Paige M., Waisner, Scott A., Pandelides, Zacharias, Garcia‐Reyero, Natalia, Erickson, Russell J., Ankley, Gerald T., Conder, Jason, Moore, David W.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.01.2024
• Subjects: Alkanesulfonic Acids - metabolism; Alkanesulfonic Acids - toxicity; Animals; Body weight; Danio rerio; Design of experiments; Ecological effects; Egg production; Eggs; Experimental design; Exposure; Fertilization; Fluorocarbons - metabolism; Fluorocarbons - toxicity; Growth; Humans; Male; Multigenerational exposure; Perfluorooctane sulfonic acid; Perfluorooctane sulfonic acid (PFOS); Public domain; Reproduction; Side effects; Statistical analysis; Sulfonic acid; Survival; Toxicology; Vitellogenin; Water Pollutants, Chemical - metabolism; Water Pollutants, Chemical - toxicity; Yolk; Yolk protein; Zebrafish; Zebrafish - metabolism; United States > US; Zebrafish; Reproduction; Growth; Perfluorooctane sulfonic acid (PFOS); Multigenerational exposure

A prior multigenerational perfluorooctane sulfonic acid (PFOS) exposure investigation in zebrafish reported adverse effects at 0.734 µg/L, among the lowest aquatic effect levels for PFOS reported to date. The present three‐generation PFOS exposure quantified survival, growth, reproduction, and vitel...