A covariate‐specific time‐dependent receiver operating characteristic curve for correlated survival data

• Published in: Statistics in medicine Vol. 39; no. 19; pp. 2477 - 2489
• Main Authors: Meddis, Alessandra, Blanche, Paul, Bidard, François C, Latouche, Aurélien
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 30.08.2020; Wiley-Blackwell
• Subjects: Biomarkers; Breast cancer; clustered survival data; covariate‐specific; discrimination; heterogeneity; Life Sciences; Santé publique et épidémiologie; time‐dependent ROC curve; covariate-specific; discrimination; time-dependent ROC curve; clustered survival data; heterogeneity

Several studies for the clinical validity of circulating tumor cells (CTCs) in metastatic breast cancer were conducted showing that it is a prognostic biomarker of overall survival. In this work, we consider an individual patient data meta‐analysis for nonmetastatic breast cancer to assess the discr...