Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium

• Published in: Pflügers Archiv Vol. 437; no. 6; pp. 812 - 822
• Main Authors: Illek, B, Tam, A W, Fischer, H, Machen, T E
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 01.05.1999
• Subjects: Adenocarcinoma; Anions; Bicarbonates - metabolism; Cell Membrane - metabolism; Cell Membrane Permeability; Cellular biology; Cyclic AMP - pharmacology; Cystic fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator - metabolism; Electric Conductivity; Epithelial Cells - ultrastructure; Fatty Acids - metabolism; Humans; Lung - ultrastructure; Lung Neoplasms; Nitrates - metabolism; Phosphates - metabolism; Propionates - metabolism; Thiocyanates - metabolism; Tumor Cells, Cultured

Anion selectivity of the cystic fibrosis conductance transmembrane conductance regulator (CFTR) and other channels and parallel pathways expressed endogenously in apical membranes of polarized Calu-3 epithelial monolayers was studied under control conditions and during cAMP stimulation. Basolateral...