Genomic Signatures of Positive Selection in Human Populations of the OXT , OXTR , AVP , AVPR1A and AVR1B Gene Variants Related to the Regulation of Psychoemotional Response

• Published in: Genes Vol. 14; no. 11; p. 2053
• Main Authors: Bakoev, Siroj Yu, Korobeinikova, Anna V, Mishina, Arina I, Kabieva, Shuanat Sh, Mitrofanov, Sergey I, Ivashechkin, Alexey A, Akinshina, Alexsandra I, Snigir, Ekaterina A, Yudin, Sergey M, Yudin, Vladimir S, Getmantseva, Lyubov V, Anderzhanova, Elmira A
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 08.11.2023
• Subjects: Adaptation; Autism; Behavior; Consortia; Emotional behavior; Genes; Genetic diversity; Genomes; genomic signatures; Genomics; Haplotypes; Hormones; Humans; Minority & ethnic groups; Natural selection; OXT; OXTR; Oxytocin; Oxytocin - genetics; Population genetics; Positive selection; Quality control; Reagents; Receptors, Oxytocin - genetics; Receptors, Vasopressin - genetics; Social behavior; Stress; Vasopressin; Vasopressins; Whole genome sequencing; United States > US; Switzerland; genomic signatures; stress; OXTR; AVPR1B; adaptation; OXT; positive selection; AVP; AVPR1A

The neurobiological systems of maintenance and control of behavioral responses result from natural selection. We have analyzed the selection signatures for single nucleotide variants (SNV) of the genes of oxytocin ( , ) and vasopressin ( , , ) systems, which are associated with the regulation of soc...