Starch-based controlled release matrix tablets: Impact of the type of starch

• Published in: Journal of drug delivery science and technology Vol. 61; p. 102152
• Main Authors: Elgaied-Lamouchi, D., Descamps, N., Lefevre, P., Rambur, I., Pierquin, J.-Y., Siepmann, F., Siepmann, J., Muschert, S.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2021; Elsevier
• Series: Journal of Drug Delivery Science and Technology
• Subjects: Controlled release; Diprophylline; Life Sciences; Pre-gelatinization; Starch; Tablet; Tablet; Diprophylline; Starch; Pre-gelatinization; Controlled release

Different types of starches were used to prepare controlled release tablets loaded with diprophylline by direct compression. The impact of the natural origin of the starch, potential chemical modifications (e.g., cross-linking with phosphate or adipate, hydroxypropylation, acetylation to different d...