Long-term safety and effectiveness of lisdexamfetamine dimesylate in adults with attention-deficit/ hyperactivity disorder

• Published in: CNS spectrums Vol. 14; no. 10; p. 573
• Main Authors: Weisler, Richard, Young, Joel, Mattingly, Greg, Gao, Joseph, Squires, Liza, Adler, Lenard
• Format: Journal Article
• Language: English
• Published: United States 01.10.2009
• Subjects: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity - drug therapy; Attention Deficit Disorder with Hyperactivity - physiopathology; Central Nervous System Stimulants - pharmacology; Central Nervous System Stimulants - therapeutic use; Dextroamphetamine - adverse effects; Dextroamphetamine - pharmacology; Dextroamphetamine - therapeutic use; Dose-Response Relationship, Drug; Electrocardiography - methods; Female; Humans; Lisdexamfetamine Dimesylate; Longitudinal Studies; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index; Time Factors; Vital Signs - drug effects; Young Adult
• ISSN: 1092-8529
• DOI: 10.1017/S1092852900024056

To evaluate the long-term safety and effectiveness of lisdexamfetamine dimesylate (LDX) in the treatment of adults with attention-deficit/hyperactivity disorder (ADHD). Following a 4-week, placebo-controlled, double-blind trial, 349 adults with ADHD were enrolled into an open-label, single-arm study...